This is a brave person. This is what bravery looks like. This is what truth looks like. This is the voice of the Middle East. I know it’s so much sexier to blame the Jews, but it’s so incredibly selfish, privileged and unintelligent.

Although it is a very exciting development, it is sad to see that no code will be released, which would not be allowed for academic institutions @nature. It was clear that weights will not be released (despite being trained purely on public data) but this I did not expect.

1. Yesterday in lab meeting we discussed the proper etiquette for how to ask for reagents. Obviously if a reagent is published it should (& in my lab will) be sent no matter how the request is made. BUT its professional courtesy to do so in collegial manner. Here's a rough guide:

Pedro Beltrao As a reviewer #3 of the paper, I tried REALLY HARD to get nature to demand downloadable code. The editors just ghosted me. I wrote extensively that the server needed work but I was not given the paper to re-review so I don't know if they improved it. It's not available yet.

AlphaFold3 is out with improvements on structural models that include DNA/RNA and small molecules. Unfortunately, there is no code, no binary to run at scale and only a limited webserver. Why even publish? nature.com/articles/s4158…

Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social nature Google DeepMind I think if there is no interest to publish the code, Deepmind should simply do a press release (which they did months ago). In the absence of that and a server with very limited throughput, this is just an Ad.

In my review, I made a list of much science that happened bc AlphaFold2 code was released. I suggested that so much science will not happen if AlphaFold3 code is not released (or not with AF3 itself). We've made ~100k models with AF2 code. How could we use a server for all that?

Delighted to share the exciting work from talented postdoc Minhoo Kim, exploring the impact of post-estropausal microbiome 💩 on ovarian ♀️ health in mice 🐁, out today in bioRxiv. Whereby we see surprising and important findings, a 🧵 1/7 biorxiv.org/content/10.110…

Instead of a large animal (mice🐀), we decided to investigate the effects of in vivo reprogramming in a smaller one (worms🪱). Happy with the results and excited about the new experiments that we are currently performing, which would take years in mice. The best is yet to come!

A seal accidentally scaring a baby polar bear is the CUTEST thing ever. 😂😭

🚨Registrations are now open for the 2024 Aging and Microbiome Conference, Jena (Germany), Oct 22-23.
We have a stellar line-up of invited speakers.
Join us in beautiful Jena to discuss about aging and the microbiome.
amc24.leibniz-fli.de
Leibniz-Institut für Alternsforschung (FLI)

People with 2 copies of APOE4 were known to have a high risk of #Alzheimers .
Today that changed to nearly 100% full penetrance
NATURE.med
nature.com/articles/s4159…

can we please stop tricking ourselves into believing data analysis is the quick part that takes a small proportion of a project? so far i have only published pure dry lab papers. there is NONE that took less than year(s). even those without new methods take long.