Great recap of the randomized trials in the 2L+ HR+ MBC setting by Eva M Ciruelos. #ESMOBreast24 #ESMOAmbassadors ESMO - Eur. Oncology

Very happy to share our Platinum Opinion on intermediate and clinically meaningful #endpoints reflecting patient benefit in localized #ProstateCancer
👉A roadmap for future endpoint development
👉authors.elsevier.com/a/1j6R%7E14kpl…
European Urology Christopher Sweeney, MBBS Stephen Freedland, MD Felix Feng

Selection of Germline Genetic Testing Panels in Patients With Cancer: ASCO Guideline

Who, when and which genetic test?

OncoAlert
ascopubs.org/doi/10.1200/JC…

Genes that should be included in germline testing panels by tumor type (including prostate cancer): ASCO guideline just published.

ascopubs.org/doi/pdf/10.120…

What are pragmatic clinical trials? Clinical trials that streamline data collection and design by collecting only necessary information to answer the research question. A thread 🧵 1/5

#ProjectPragmatica #OCEProject5in5 #PragmaticTrials

Don’t forget to register!! We have confirmation of:
- Argentina 2 teams
-Brasil 2 teams
- Colombia 1’team
- USA 1 team
- France??
- Spain 1 team
- Australia?
- the tournament is aproaching
Next Monday 18.00 hs

Toni Choueiri, MD FabriceAndre Neeraj Agarwal, MD, FASCO ASCO #ASCO24

🔥⚽️🔥 the most funky, friendly, fashioned social event of the oncology community is como back again this year! 🚀🚀 The #ASCO24 football tournament. The latest versions were a lot of fun. 😎 Don't miss it and sign up!🔥
With a rock stars Toni Choueiri, MD and FabriceAndre OncoAlert

Annual meeting of the CARE 1 metastatic 1st line RCC study which is open in France 🇫🇷 and will open in 🇬🇧 soon. Biomarker driven trial (PD-L1) of ipi/nivo vs VEGF/PD1 Laurence Albiges . The Barts team in Paris enjoying the sunshine !!

DARIUS trial protocol is online in European Urology Oncology
▶️Phase 2 randomized
▶️ Unfavorable intermediate risk prostate cancer
▶️ Radiotherapy + stADT Versus an ADT sparing approach using stDarolutamide
▶️58/62 patients included...
▶️PSA End as 1st objective
sciencedirect.com/science/articl…

Repost if you think Ricky Gervais should host another awards show.

OpenFold developed by Gustaf Ahdritz, Nazim Bouatta, and Mohammed AlQuraishi is a trainable, open-source implementation of AlphaFold2. It is fast and memory efficient, and the code and training data are available under a permissive license.
nature.com/articles/s4159…

Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies.
bit.ly/3yhfMk2

The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia dlvr.it/T6tmsG

📌¡¡¡Qué poco queda!!!
👉Este jueves 16 de mayo celebramos el #VCursoAnualdeUC en Madrid
Una oportunidad de profundizar en el conocimiento y establecer nexos de investigación en #CancerdeVejiga
APUNTATE!!!👇👇
tacticsmd.net/actividad/v-cu…

📍Keynote-057 Cohort B (Phase-2)

📍Pembrolizumab monotherapy IV 200 mg/3 weeks up to 35 cycles

📍High-risk non-muscle-invasive bladder cancer (High grade Ta, any grade T1) without carcinoma in situ and unresponsive to BCG

➡️12-month disease-free survival was 43·5% (95% CI

A #CryoEM structure of VMAT2, a transporter in synaptic vesicles, reveals the mechanisms of drug and neurotransmitter binding, inhibition, and transport. elifesciences.org/articles/91973…

👏👏 Latin American Consensus on the Treatment of Head and Neck Cancer | JCO Global Oncology ascopubs.org/doi/10.1200/GO…? @aaoc The ASCO Post @lacog_group @@intcmp=cc_ascoorg_jgo_may2024_site_homepage_all__glob_050124__praccngsci__aware_text_may2024

A new PET imaging agent yielded high-quality PET scans of metastatic ccRCC tumors in as little as one hour. In a new study in JNM, research shows that CAIX tracker Debio 0328 cuts down on the time it takes patients to get a scan. Read more: jnm.snmjournals.org/content/65/5/7…

👏👏👏 congrats!!