Fantastic overview of H2H trials in IBD. More on the way this DDW. Great work Beatriz Gros

I am so thrilled that our study defining mechanisms of #PerianalFistula in #Crohns disease is now out in Med by Cell Press . Thank you to Judy Cho + team, Mount Sinai IBD Center MountSinai Pathology SinaiMSTP , and the patients who made this possible
doi.org/10.1016/j.medj…

As we near 550 participants in the multi-omic precision medicine study IBD-RESPONSE, thanks to BMJ_Open for publishing our protocol - patient pathway and analytical plans for microbiome, single cell transcriptome, genetics, metabolome and diet - bmjopen.bmj.com/content/14/4/e…🦠🍏🧬 🙏

Beatriz Gros Fernando Gomollón Sociedad Española de Patología Digestiva (SEPD) Ashkan Rezazadeh MD Aline Charabaty, MD, FACG, AGAF Seb Y-ECCO ignacio catalan Guillermo Veitia V. GETECCU Joseph Sleiman, MD My main skill is appreciation of talent and hard work in others.

Your website is amazing!

Beatriz Gros Fernando Gomollón Sociedad Española de Patología Digestiva (SEPD) Ashkan Rezazadeh MD Aline Charabaty, MD, FACG, AGAF Seb Y-ECCO ignacio catalan Guillermo Veitia V. GETECCU Joseph Sleiman, MD Amazing summary.. each one is for keeps.. thanks for sharing!!

The May issue of CGH is out!

😮Any authors you would like to hear more from about a particular publication?

📞Let us know and we can host them for a live talk for Q&A about their path to publication success with #CGH4ALL

🔗 cghjournal.org/current#closeF…

First-line infliximab #biosimilar in paediatric Crohn's disease cost effective! See our latest paper
onlinelibrary.wiley.com/doi/10.1111/ap…

Happy Earth Day! A shocking proportion of the habitable land on 🌍 is used exclusively to produce meat and dairy. You can change this. Learn more: ourworldindata.org/land-use-diets

Dermal injury drives a skin to gut axis that disrupts the intestinal microbiome and intestinal immune homeostasis in mice ⁦Nature Communications⁩ nature.com/articles/s4146…

Step-up vs Step-down Elimination Diet for Eosinophilic Esophagitis

▪️Step-up makes sense
▪️Especially, EoE ➡️ ❌🦀
▪️Start with SINGLE food or TWO food
▪️If ❌ response, FOUR food
▪️Then consider SIX food
▪️6 weeks for each

🔗 gastrojournal.org/action/showPdf…

🙏Joan Chen, MD MS

#EBMed

Sometimes I get asked about stem-cell transplantation (SCT) for IBD

☑️The Lancet Gastroenterology & Hepatology 👇🏾

🟢bold idea + brave pts + investigators.

🔴 risk of SCT >>>> risk of IBD
🔴SCT not better than standard tx

🔴don’t trade morbidity for mortality?

thelancet.com/journals/langa…

Welcome Y-ECCO to USA & #EBMed

Happy to see Youth committee leads here as travel grant awardees Maria Manuela Estevinho & Virginia Solitano

We need more interactions across the ponds & beyond Seb Lumír Kunovský Paula Sousa my_UEG Aline Charabaty, MD, FACG, AGAF Ashkan Rezazadeh MD Beatriz Gros ignacio catalan

Unappreciated MOA of vedolizumab with major implications including new perspectives for precision medicine

Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis. pubmed.ncbi.nlm.nih.gov/38640252/

Fascinating study on Vedolizumab mechanism of action in Ulcerative colitis in Science Immunology by Mehandru Lab @MountSinai

Saved for reading after the weekend!⛵️

👇🏻👇🏻👇🏻

In this US veterans cohort study with incident #IBD , incident use of TNF inhibitors was independently associated with higher risk of kidney function decline 🤔

👫 10 689 patients

-aHR, 1.34 [95% CI, 1.18-1.52]

Thoughts?

jamanetwork.com/journals/jaman…

Great diet trial published yesterday!
294 people with #IrritableBowelSyndrome #IBS

1⃣Low FODMAP plus BDA/NICE (76% responders)
2⃣Low carbohydrate (71%)
3⃣Optimised medical (58%)
P=0.023

Paper Magnus Simren in The Lancet Gastroenterology & Hepatology

thelancet.com/journals/langa…
#IBS AwarenessMonth #CFGI24

🔸What’s the pathophysiology of Portal Hypertension?

🔹Which therapeutic options are available or in the pipeline?

🔸Can we optimize the research in this field?

✅Answer these, and other, questions in our latest review now available The Lancet Gastroenterology & Hepatology

🆓 authors.elsevier.com/a/1ixqA8nByr8u…