Fantastic that the Science and Innovation at Cancer Research UK funded STAR TREC organ preservation rectal cancer trial has completed recruitment of >500 patients! A real privilege to co-lead with Simon P Bach and work with amazing colleagues across Europe. A big thank you to the patients who participated.

👏 Congratulation to Pam Kearns on winning a Lifetime Achievement Award at the Children’s Cancer and Leukaemia Group conference. The award recognises Pam's exceptional leadership and commitment to children’s & young people’s cancer care and research.

Uni of Birmingham | Bham Children's Hosp 💙 | Birmingham Experimental Cancer Medicine Centre | Birmingham Cancer Research UK Clinical Trials Unit

🎉 Congratulations to Prof Pam Kearns for winning the #LifetimeAchievement Award at #CCLGMemberAwards ! 🏆 Leading in paediatric cancer care & #research , Pam's dedication to #PaediatricOncology is truly exceptional 🌟 #CCLG2024  
Pam Kearns 
Uni of Birmingham

Congratulations to Prof Gary Middleton, Director of our Birmingham Experimental Cancer Medicine Centre Birmingham Experimental Cancer Medicine Centre who has been appointed as Network Lead across all ECMCs!
Please join us in congratulating him on this fantastic appointment👏
➡️bit.ly/4anZDqq
#CancerResearch

We're pleased to share this video of Prof Adrian Bloor, RATinG Chief Investigator, from the perspective of a patient asking questions about the #clinicaltrial of Lenzilumab for acute Graft vs Host Disease #aGvHD Birmingham Cancer Research UK Clinical Trials Unit Open @ 13 UK hospitals
youtu.be/QwPyeXqwyrc?si… via YouTube

1st patient has been recruited to LIBERATE randomised, double-blind Phase 2b #clinicaltrial of #glenzocimab for #HeartAttack in partnership with Acticor Biotech. LIBERATE will enrol >200 patients diagnosed with ST-elevation myocardial infarction (STEMI) University Hospitals Birmingham & Sheffield Hospitals

we also published the results from Wisteria, a phase I #clinicaltrial combining AZD1775+cisplatin in head & neck cancer. Wisteria used a novel design, mTITE-CRM, that could be used in trials with complex patient populations
#WorldCancerDay InHANSE RESEARCH
nature.com/articles/s4427…

last week we closed CompARE #clinicaltrial after recruiting 794 head & neck cancer patients. A huge achievement made possible from the support of our NHS sites, Science and Innovation at Cancer Research UK & our patients. The protocol paper is available trialsjournal.biomedcentral.com/articles/10.11…
#WorldCancerDay InHANSE RESEARCH

This #WorldCancerDay we’re highlighting the BEACON trial, which found that children who develop #neuroblastomas may benefit from receiving certain anti-tumour drugs as well as chemotherapy. birmingham.ac.uk/news/2024/comb… Birmingham Cancer Research UK Clinical Trials Unit Institute of Cancer and Genomic Sciences (UoB) Uni of Birmingham

in 2023 we opened the ARISTOCRAT phase II #clinicaltrial of temozolomide with or without cannabinoids in patients with recurrent #glioblastoma at 10 UK hospitals, funded by The Brain Tumour Charity. The protocol was recently published in @BMC Cancer
#WorldCancerDay
bmccancer.biomedcentral.com/articles/10.11…

last week we published PARC #clinicaltrial results showing that arginine depletion is safe in relapsed/refractory cancers of children & young adults. This strategy may have potential for future trials in combination with other drugs #WorldCancerDay
frontiersin.org/journals/oncol…

today is #WorldCancerDay , a time for those of us in cancer research to pause & reflect on the progress we have made in the past year. Also a time to remember everyone we have sadly lost to cancer, and those who have participated in research to help others in the future ❤️

earlier in 2024, we published the methodology of a novel dose finding statistical design (PO-TITE-CRM) for ADePT-DDR, a phase I head & neck #clinicaltrial using AZD6738 (ATR inhibitor) + radiotherapy
#WorldCancerDay InHANSE RESEARCH bmcmedresmethodol.biomedcentral.com/articles/10.11…

Professor Amos Burke, recently appointed Director of the Birmingham Cancer Research UK Clinical Trials Unit explains the promising areas and challenges of #CancerResearch , as well as his hopes for the future of the trials unit. #WorldCancerDay birmingham.ac.uk/research/crctu… Uni of Birmingham Institute of Cancer and Genomic Sciences (UoB)

Promising results from the #ClinicalTrial BEACON, led by Birmingham Cancer Research UK Clinical Trials Unit, showed that combining Bevacizumab with standard chemotherapy improves treatment response in children & young people with relapsed or refractory #Neuroblastoma . Read more 👉 bit.ly/3tSLuSA

Uni of Birmingham

The BEACON trial – led by the Birmingham Cancer Research UK Clinical Trials Unit – shares results in the Journal of Clinical Oncology that show how combining anti-tumour drugs with chemo could lead to more young people with neuroblastomas seeing their tumours shrink. Solving Kids' Cancer UK 🎗 Imagine for Margo Science and Innovation at Cancer Research UK Institute of Cancer and Genomic Sciences (UoB) birmingham.ac.uk/news/2023/comb…

Welcome to Professor Amos Burke, who was recently appointed Director of the Birmingham Cancer Research UK Clinical Trials Unit Birmingham Cancer Research UK Clinical Trials Unit Institute of Cancer and Genomic Sciences (UoB) birmingham.ac.uk/news/2023/prof…

Proud to celebrate 25 years of UKTMN at Uni of Nottingham #WeAreUoN today; supporting trial management professionals at both Birmingham Cancer Research UK Clinical Trials Unit and Birmingham Clinical Trials Unit Uni of Birmingham Medical and Dental Research (UoB)

Thank you to everyone who came to our Patient & Public engagement day!
It was amazing! 😃The Giles' Trust Colin Watts brainstrust Brain Tumour Support 💙 Tessa Jowell Brain Cancer Mission UHB Neurosurgery University Hospitals Birmingham Institute of Cancer and Genomic Sciences (UoB) The Brain Tumour Charity Josh the Savage 🇺🇦

Dr Josh Savage from Birmingham Cancer Research UK Clinical Trials Unit Uni of Birmingham what does a Clinical Trials Unit do?