Inhibitory signalling pathways in T cells are often understudied. We have a high-throughput way in which signalling by important inhibitory molecules can be interrogated! life-science-alliance.org/content/7/3/e2…

What does it mean for a T-cell to be 'exhausted'? How are exhausted T-cells being generated and studied and how can we start to introduce the microenvironment into exhaustion research? Check out our new review: Martin Fellermeyer Toby Whitehead Edward Jenkins

Got a big itch to study T-cell exhaustion!!??

Our review has got your back! We include:

🙆The latest updates in exhaustion🙆
🧪In vivo/vitro models of exhaustion🧪
📊How to best verify in vitro exhausted T cells📊
📈The future of in vitro approaches📈

doi.org/10.1093/oxfimm…

Our post-doc Sumana Sharma gives a quick introduction to her research as part of the 1st European Cancer Dependency Map Symposium!

Researchers at Davis Lab Oxford investigate the potential of a new combination #immunotherapy of #nivolumab , a clinically approved #PD1 blocking antibody, & OX108, a #CD200R blocker

Explore their results in mouse models for colorectal & lung #cancer ➡️bit.ly/3Madlmm

Great opportunity for Matt Kotowski and Markus Körbel! @MRC_HIU RDM Oxford MRC WIMM

Very pleased to have my first PhD publication published in Immunotherapy Advances Journal. Using humanised mice we trialled the combination immunotherapy of nivolumab and OX108 (a CD200R blocker) in two tumour models.
Davis Lab Oxford Cornall_lab @MRC_HIU MRC WIMM RDM Oxford

Check out mine & Markus Körbel work in Nature Communications. We address a long-standing question in T cell biology - how to discriminate between antigens. It turns out the shape of T cells is key!

nature.com/articles/s4146…

#Immunology #Tcell #microvilli Davis Lab Oxford KlenermanLab

Today was my last day in the Davis Lab Oxford! I've truly enjoyed my time there over the last 5 years (!) but I'm excited to be starting a postdoc in Ricardo A. Fernandes in a different field of T-cell biology.

We are recruiting a new research assistant!
jobs.ac.uk/job/CTT259/res…

Congratulations Toby for completing the London Marathon today in aid of Sarcoma UK. An amazing achievement. One final push for donations! justgiving.com/fundraising/To…

Please donate to our student Toby's marathon fundraiser

The Ling Felce Bioinformatics Suite was opened yesterday at CAMS Oxford Institute in memory of Ling.

A fund in her honour aims to offer financial support for researchers seeking bioinformatics training.

For more information and to donate, please visit: camsoxford.ox.ac.uk/about/the-ling…

Yesterday we officially opened the Ling Felce Bioinformatics Suite here at the CAMS-Oxford Institute (Nuffield Department of Medicine). In addition to the Ling Felce Award (camsoxford.ox.ac.uk/about/the-ling…), this will ensure Ling’s legacy continues for years to come.

Another great presentation from our postdoc Sumana Sharma at the Oxford Immunology Group meeting this morning!

Congratulations to Caitlin O'Brien-Ball for passing her viva! We celebrated with cake and champagne 🍾 🎂

We have a PhD project focused on understanding T cell antigen discrimination. Please consider joining our fantastic team and department!
findaphd.com/phds/project/u…

science.org/doi/10.1126/sc…

In memory of Dr Felce, the Ling Felce award will help to support the next generation of world-leading computational biologists.

CAMS Oxford Institute Nuffield Department of Medicine University of Oxford

imm.ox.ac.uk/news/fundraisi…

I am delighted to share our new accelerated PAINT technique, called resPAINT, now published in Angewandte Chemie.

onlinelibrary.wiley.com/doi/10.1002/an…

Just in time for my talk at #SMLMS2022

Thanks to the hard work of all authors and excellent mentoring from Steven F. Lee and Aleks Ponjavic