It's out! We report 3D mapping of human pancreatic precancer and associated genetic alterations. With the brilliant Ashley Kiemen and Denis Wirtz . Tweetorial to follow soon. nature.com/articles/s4158…

Folks, the new MD Anderson Cancer Center Faculty Collaborative Space is AMAZING! Time for some coffee, biscuits and brainstorming.

Using #scRNAseq and preclinical models in a study funded by #NCICSBC , Guangchun Han, Ansam Sinjab 🇺🇸🇸🇾🇱🇧, Linghua Wang, MD, PhD, Humam Kadara, et al. generated an atlas of epithelial cell states and plasticity in #LungCancer nature nature.com/articles/s4158….

Very wonderful experience AACR 2024. Thanks so much for the supervision from my great mentors Linghua Wang, MD, PhD Amir Jazaeri , and the efforts from my fantastic collaborator Anne Knisely, MD. We will keep working on ovarian cancer MRD, aiming to find a cure! MD Anderson Cancer Center

Building a multimodal spatial-omics atlas could point to targets for early detection or interception of #LungCancer . 

Our fellow Dr. Ansam Sinjab shares findings at #AACR24 : bit.ly/3VMoJeP Ansam Sinjab 🇺🇸🇸🇾🇱🇧 Linghua Wang, MD, PhD Humam Kadara AACR #EndCancer

⁦Laura DeLong Wood⁩ shows the power of 3D sectioning and AI to characterize the heterogeneity and burden of PanINs - transformative for our understanding of precancer formation ⁦AACR⁩ #AACR24

✨Highlighting a Cancer Discovery Special Issue Commentary for #AACR24 : The 3D Revolution in Cancer Discovery - by Linghua Wang, MD, PhD Mingyao Li & Tae Hyun Hwang doi.org/10.1158/2159-8… MD Anderson Cancer Center Penn Mayo Clinic

Outstanding presentation by Susan Bullman on spatial microbial microniches. #AACR2024 #ASCO #fightcrc

Ludwig Harvard Medical School's Peter Sorger gave a visually (and intellectually) arresting talk at the #AACR24 plenary session on the use of multiplex, 3D imaging and spatial profiling to analyze the immune landscape of melanoma tumors.

Phenomenal plenary choice by #AACR24 AACR

So proud of mentee Xinmiao Yan for receiving an AACR Scholar in Training Award #AACR24 . Stay tuned for more on her work unraveling the immune hallmarks of #RenalMedullaryCarcinoma .

Mapping the Pre-Cancer Atlas provides valuable insights that help us better understand cancer cells and identify therapeutic targets.

Meet Drs. Nick Navin and Linghua Wang today, April 8 from 1-1:30 p.m. to learn more. Nicholas Navin Linghua Wang, MD, PhD #AACR24 #EndCancer

Discuss the latest research on synergies in immunology with Drs. Michael Curran and Linghua Wang at #AACR24 Booth 1239 today, April 7 from 2-2:30 p.m. Michael A. Curran, Ph.D. Linghua Wang, MD, PhD AACR #EndCancer

What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24 , out in Cancer Discovery today rb.gy/q484j9 Tweetorial👇

One might assume that there is a widely adopted playbook of best practices for cancer team science. But no such playbook has existed—until now! A new commentary on the modern era of cancer research from Jacks Lab Jesse Boehm #RadicalCollaboration Cancer Discovery aacrjournals.org/cancerdiscover…

Non-destructive imaging tech like Holotomography TOMOCUBE, INC. offer detailed view of both cellular and non-cellular components, including ECM structure within TME. This tech allows for preservation of tissue integrity, enabling subsequent analyses such as single-cell sequencing

Thank you Linghua Wang, MD, PhD Mingyao Li & Tae Hyun Hwang for responding to the Cancer Discovery call for commentaries! I'm so excited to finally be able to share the collection with the community and highlight the pieces during #AACR24 !

What are the hallmarks of Precancer?
See our commentary in Cancer Discovery from the NCI Division of Cancer Biology TBEL Consortium (tbelprogram.org/index.html) driven by an exceptional cache of trainees & early career investigators.
aacrjournals.org/cancerdiscover…
Ken Lau Lab Lyssiotis Lab Jimin Min