Join our faculty: ebi.ac.uk/research/groups - our 9-year tenure nurtures our group leaders to go on to do great things: Virginie Uhlmann Moritz Gerstung Oliver Stegle MarioniLab Teichlab Pedro Beltrao

Mark you calendars!

Next Cambridge Computational Oncology Meeting is May 5 at the EBI in Hinxton.

Speakers: Hillary Elrick Hillary Elrick , Alex Gutteridge Alex Gutteridge and Peter Campbell

Happy to present my recent work - a cluster-free method for DE testing, leveraging overlapping neighbourhoods in the graph representation of sc-data (aka miloDE): biorxiv.org/content/10.110… . A little thread below describes the motivation and suggestions on interpreting the results.

The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer.

ebi.ac.uk/about/news/res…

Excited to share Carine Stapel and my #singlecell #singleorganoid time course of #gastruloid development. We reveal substantial inter-organoid heterogeneity, and show why understanding it is critical in #organoid #perturbation experiments. A #tweetorial (1/18)

AlphaFold DB will boldly go where no scientist has gone before.

With over 200 million protein structure predictions added to the database, AlphaFold DB now gives users open access to a 3D protein universe. #AlphaFold @DeepMind

ebi.ac.uk/about/news/tec…

A magical week at the Marioni Lab retreat - a blessing of (purple) unicorns indeed and many (uni)corny jokes

John Marioni has been elected as a new Fellow to the Academy of Medical Sciences 👏 in recognition of his remarkable contributions to biomedical science and the generation of new knowledge to improve the health of people everywhere. #AMSFellows2022

We're hiring!

Looking for an enthuastic postdoc to join the team and work with single-cell genomics data to construct and compare senescence trajectories for cells. Deadline 22nd Feb embl.org/jobs/position/…

The new @EMBL Programme has launched!

We're proud to be a part of @EMBL and we're looking forward to contributing our #bioinformatics expertise to this exciting new scientific programme that ushers in a new era in the life sciences.

For a lay summary of our new method to study #transposableelement expression with long read sequencing in single cells please read this post

Very happy that our single CELl LOng read RNA sequencing (CELLO-seq) method for locus-specific #TransposableElement expression is out in
Nature Biotechnology today! Find the paper here: nature.com/articles/s4158… 1/n

Congratulations to @Blavatnikawards 🇬🇧 Finalist 🏅 Finalist in Life Sciences Dr. John Marioni MarioniLab EMBL-EBI CRUK Cambridge Institute #Blavatnik2021 bit.nyas.org/3n0x0Yb #computationalbiology #RNAtranscription

What are the ripples of making data #openaccess ? A recent independent report quantified these efforts to explore the role of #opendata in the life sciences today. #OAweek #opendata
ebi.ac.uk/about/our-impa…

Differential abundance testing on single-cell data using k-nearest neighbor graphs go.nature.com/2Y69iSH

📢Our work on differential abundance analysis in single-cell data with Milo is now out in Nature Biotechnology🤩🎉 a fantastic team effort with @MDMorgan_cam nature.com/articles/s4158…

Highlights on updates since the preprint👇(1/6)

Still time to apply for our new postdoc position using computational approaches to study developmental trajectories across species. Deadline 19th September jobs.cam.ac.uk/job/31028/

NEW POST: We (virtually) sat down with John Marioni, new collaborator on the Cancer Grand Challenges IMAXT programme EMBL-EBI CRUK Cambridge Institute Wellcome Sanger Institute to find out more about his work and what excites him about the project. Read more - bit.ly/3svUnMP

We're looking for a new postdoc in the Marioni group - a two year position to work on developmental trajectories across species using single-cell approaches and data integration methods jobs.cam.ac.uk/job/31028/

Congratulations to Alsu amissarova! Fantastic work.