New content online: Sertoli cell lysosomal dysfunction drives age-related testicular degeneration dlvr.it/T7Gcv1

New content online: Obesity dysregulates a pituitary–liver axis through disruption of the unfolded protein response dlvr.it/T7D1Jz

New content online: Transcriptional control of metabolism by interferon regulatory factors dlvr.it/T798pp

New content online: AMPK as a mediator of tissue preservation: time for a shift in dogma? dlvr.it/T73NYR

A perspective on treating type 1 #diabetes mellitus before insulin is needed, from Danijela Tatovic, Parth Narendran & Colin M. Dayan (£) go.nature.com/3nZ0204

Here, Thomas Lutz outlines the advantages and disadvantages of selected animal models of #diabetes mellitus (£) go.nature.com/42phtGB

This Review from Catherine Postic and colleagues discusses mechanisms that regulate #ChREBP activity, the role of ChREBP in #NAFLD and emerging NAFLD drug targets (£) go.nature.com/3o4kn4k

This Review from Tina Vilsbøll and colleagues highlights mechanisms of #glucagon secretion from pancreatic α-cells, including paracrine actions in islets and α-cell–β-cell crosstalk (£) go.nature.com/40mjukZ

In our latest issue: Florent Sauvé, Loïc Kacimi & Vincent Prévot discuss the hypothalamic–pituitary–gonadal axis and the enigma of #Alzheimer disease sex differences rdcu.be/dH67p

From our June issue: H. Eric Xu and colleagues discuss the use of cryo-electron microscopy for #GPCR research and drug discovery in endocrinology and metabolism (£) go.nature.com/3uRbU82

In our latest issue: Mirela Delibegović, Sergio Dall’Angelo & Ruta Dekeryte review the role of protein tyrosine phosphatase 1B in #metabolic diseases and drug development (£) go.nature.com/3ITjPoo

From our June issue: a Review providing an updated summary of evidence regarding #COVID19 and #thyroid dysfunction (£) go.nature.com/3SMhcJT
David Lui 呂德威 Paul Lee YC Woo Ivan Hung, MD FRCP (Lon,Edin) HKU Medicine HKU Department of Medicine

The Nature Reviews Endocrinology June issue is now online! Check out articles on #obesity & the #kidney , #thyroid & #COVID19 , cryo-EM, and protein tyrosine phosphatase 1B nature.com/nrendo/

New content online: The role of brown adipose tissue in metabolic health dlvr.it/T6tXdl

The ultimate bioengineering challenge - take part now! We are launching a competition asking students and Postdocs to theoretically tackle some of the most pressing bioengineering challenges – from the idea to the sketch of a prototype.
More info here: go.nature.com/4dCP2KW

New content online: Hearing abnormalities in patients treated with teprotumumab dlvr.it/T6qt9s

New content online: Advances in the management of achondroplasia dlvr.it/T6qt7g

New content online: Publisher Correction: Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency dlvr.it/T6cLz0

New content online: Author Correction: Targeting the incretin system in obesity and type 2 diabetes mellitus dlvr.it/T6YQPP