Commencing #BrainTumorAwarenessMonth by gathering Pediatric Neuro-Oncology experts worldwide, with gratitude to @danafarber for hosting us! Appreciating all who joined, whether virtually or in person. Anticipating continued progress following a fruitful meeting! #BTAM #PNOC

After elaborate discussions yesterday, Day 2 concluded with updates from our Working Groups. Grateful for their ongoing dedication in advancing PNOC's mission 🤝. For more info on our groups, click: pnoc.us/research-group…
Pictured: APPNIC, DEI, DMG-ACT and Medulloblastoma WGs

More from our meeting: Dr. Danielle Bitterman's (Harvard Medical) insightful talk on 'AI's Potential for Clinical Trials' has sparked exciting discussions as we explore the continued use of technology to transform research and patient outcomes💡 #AI #ClinicalTrials #Innovation

Good afternoon from Boston! Day 2 of our meeting at Dana-Farber starts with some exciting updates from our PNOC team and presentations by other brilliant investigators (Pictured: Ashley S Margol, Cassie Kline, MD, Aubrie Drechsler, Rebecca Ronsley, MD and Dr. Zeng-Jie Yang)

A very warm welcome from Boston to our phenomenal PNOC investigators as we kicked off our Spring Meeting🧠Time to dive into innovative research and collaborations driving pediatric neuro-oncology forward! #BostonBound

It’s a privilege to be part of this incredible team of international PNOC researchers driven to cure #DIPG #DMG . Thank you Alonso Lab & Clínica Universidad de Navarra for hosting us in Madrid and honored to represent Seattle Children's & the #VitanzaLab . Great progress & so much to do.

PNOC #ATRT group is advancing with our first trial for this critical patient group! Johns Hopkins' preclinical data strongly indicates efficacy of paxalisib with gemcitabine for #ATRT . Updates to follow! Eric H. Raabe, MD, PhD Kazia Therapeutics Tom Rosenberg Alyssa Reddy Ashley S Margol Susan Chi

Encouraging preliminary interim Overall Survival data for #PNOC022 was presented by Dr. Sabine Mueller at #SNO2023 . Analyses continues and we look forward to begin enrolling new patients soon! Special THANKS to the patients and families who are participating in the study.

‼️ #SNO2023 simultaneous publication in #JCO by Mueller, et al:

Everolimus for Children with Recurrent or Progressive Low-Grade Glioma: Results from the Phase 2 PNOC001 Trial. brnw.ch/21wEyjN

PNOC001, our Phase II Study of everolimus for recurrent or progressive low-grade gliomas in children is now published! A huge congratulations to the team!
Read more at: ascopubs.org/doi/10.1200/JC…

#PNOC_kids is excited to present at #SNO2023 on the combination of ONC201+paxalisib in children & young adults with DMGs after completing RT. Preliminary results show that immediate OS significantly exceeds control data. Chimerix, Inc. Kazia Therapeutics ChadTough Defeat DIPG Foundation PNOC Foundation SNO

New treatments for pediatric low-grade gliomas #pLGGs are offering hope for children with this #braintumor . Understanding the genetic changes that cause pLGGs have led to targeted therapies that were not possible before. #BTAM PNOC PNOC Foundation buff.ly/42GLAZm

Diffuse Midline Glioma ( #DMG ), including ( #DIPG ), is an aggressive tumor of the CNS with no known cure. To provide the best care for DMG patients, connecting early on with a specialized interdisciplinary team is crucial. buff.ly/42G41gQ PNOC PNOC Foundation #BTAM

An inspiring and beautiful song, indeed! Follow the link to read more on Marin Independent Journal about this: marinij.com/2023/05/07/mil…

Follow the link to read the full special issue and join us in shaping the future of care for children with brain tumors #PediatricNeuroOncology #ChildhoodCancer #OpenScience #Neoplasia #DMG #ATRT #Ependymoma #Medulloblastoma

Big news for the pediatric neuro-oncology community! Publications from @CBTNetwork and PNOC researchers are available in a special issue of Neoplasia! In honor of #BTAM , we'll be sharing articles throughout May. PNOC Foundation View here: buff.ly/3HQr8gv

Thank you to everyone who attended our annual meeting this year. We appreciate everyone’s support and efforts in our clinical trials and advancement in pediatric neuro-oncology.

We appreciate Dr. Elizabeth Blackburn for taking the time out to address our PNOC meeting!

Dr. Ashworth ends with “Working together you can overcome the difficulties of a rare condition.” And that while he expects many advances in the next 10 years, but hopes we are all done before the 30th anniversary of PNOC Foundation . Me, too!! UCSF Health #btam

Dr. Alan Ashworth says it’s all very well to do good research but if you don’t translate it, it goes nowhere. Stresses UCSF Benioff SF commitment to cancer research and children. #btam