Amazing postdoc Eric Aird asked how #CRISPR gRNAs & interferon regulate innate #immunity . He found a wild partnership that balances appropriate response w/ cell death. SP100 builds filaments that kill cells, and SP110 breaks them to keep things in line. biorxiv.org/content/10.110… 🧵

Dear community, we are very happy to announce the next Giin webinar!! Don't miss it on Tuesday, April 9th, from 5PM Rome (11AM NYC), with Stephen Jackson Steve Jackson Lab and Simona Giunta Simona Giunta. Zoom link: uniroma1.zoom.us/j/95149984403

A tremendous example of work by CRUK Cambridge Institute researchers making its way from the lab bench towards the patient beside 👏

Mission Therapeutics was co-founded by Steve Jackson Lab in 2011 with a focus on translating DNA repair research into potential therapeutics.

👇cambridgeindependent.co.uk/business/missi…

Mission Therapeutics raises £25m with two drug candidates ready for clinical trials cambridgeindependent.co.uk/business/missi…

Congratulations to Insmed, finalists in the 2024 Cambridge Independent Science and Technology Awards, Employer of the Year category, cambridgeindependent.co.uk/business/final…

'I’m delighted with the news from Mission Therapeutics about MTX325 entering into a clinical trial, and hopeful that this will lead to a much needed treatment for patients with Parkinson’s disease' says founding scientist Steve Jackson.

.Aldo Bader and Eugenia Arrieta-Sanz joined CRUK RadNet Cambridge for an exciting weekend of activities Cambridge Festival

We are delighted to have been a part of this study, the culmination of a long-standing collaboration with Gabriel Balmus and David Adams

Our world-leading researchers have backed Cancer Research UK 's call for urgent investment in cancer research, to enable #MoreResearchLessCancer .

Read more about the call, signed by Prof Sir Steve Jackson, Prof Greg Hannon and Prof Richard Gilbertson 👉 cruk.cam.ac.uk/world-renowned…

Our European Research Council (ERC) funded student, Jordan Wilson, presenting at EMBO Events ' #Evolution and diversity of the #DNA damage response', Lonavala, India

Forget your New Year's exercise resolutions....read about 'Exorcise' instead

Celebrating the New Year with a bit of tenpin bowling

WHY JOIN THE CANCER RESEARCH UK CAMBRIDGE INSTITUTE?

In our new video, four members of the team share what makes our Institute such a unique place to work.

Keep an eye on our careers page for opportunities to join the team!

➡ lnkd.in/eAfWHCHq

youtu.be/sdv9KOadrQk?si…

Our lab's latest is now out on BioRxiv. In this work we set out to understand how 'shieldin' regulates #DNArepair , focusing on its physiological function in B cells & pathological contributions to BRCA1-mutant cancers. Some background & take-home msgs (1/) biorxiv.org/content/10.110…