Great to announce that teams UCL Queen Square Institute of Neurology and Dementias Platform UK have both been awarded the Blood Biomarker Challenge. The UCL team will test the diagnostic utility of ptau217 for Alzheimer’s in @NHS memory clinics
Alzheimer's Society Alzheimer's Research UK NIHR Research BBC Radio 4 Today UK Dementia Research Institute

🚨New Paper🚨 now published in the European Journal of Epidemiology from my PhD.

Life‑course social participation and accelerometer-based physical activity in midlife using #BCS70

👉link.springer.com/article/10.100…

Key points 🧵

Great couple of days representing MRC LHA @ UCL at #ARUKConf24 with Dylan Williams, Caterina Felici, and Dr Sarah-Naomi James 🏴󠁧󠁢󠁷󠁬󠁳󠁿.

So glad we all found the time to take this definitely not photoshopped photograph together!

Come see my poster 1.52 at #ARUKConf24 today -- based on our medrxiv preprint using data from 171k folk in @ukbiobank, I'll explain why apoE is the predominant cause of most Alzheimer's disease, and why this has been overlooked. A brief 🧵...
medrxiv.org/content/10.110…

I’ve been very fortunate to be involved in over 20 Neuroimaging PIA webinars but this is the one I’m most excited about. With Derek K Jones, Yakeel T. Quiroz, PhD (she/her), Udunna Anazodo Adam M. Brickman Shana D. Stites, we will disucss how to make neuroimaging more accessible in dementia

There is a crisis in clinical academia in the UK. We talk of the need to expand medical schools, embed research into the NHS to improve care, & the importance of a vibrant life sciences sector for the economy of the UK, & yet we seem unable to tackle the underlying issues 1/9

As part of my new fellowship I am looking to fill 2 roles! See dets and links below👇

Check out Vascular Cognitive Disorders PIA's next webinar re. neuroimaging 🧠biomarkers from MarkVCID. Go here to register 👉 training.alz.org/products/4667/…

Cortical thinning in regions typically associated with Alzheimer’s may relate to vascular disease! Our latest from MRC LHA @ UCL Insight 46 study *open access* in Journal of Neurology, Neurosurgery and Psychiatry jnnp.bmj.com/lookup/content…

We were delighted with Dr. Natalia Goncalves's discussion on the notable works in our field published over the last year! Would you like to access the list of publications? Just Scan this QRcode or use the link below! #ReservePIA

Great overview by Prof Naomi Allen of the UK Biobank's cognitive data

#UKBSC23 UK Biobank

📢Our paper on the estimation of the effect of weight change on a health outcome was published in
International J Obesity!

nature.com/articles/s4136…

#epitwitter #causaltwitter
UCL Institute of Cardiovascular Science
MRC LHA @ UCL

📢Join DEMON Network Biomarkers WG next Wednesday 1st November @10am GMT. We are excited to host three speakers from the MRC LHA @ UCL: Dr Becki Green, Caterina Felici & Dylan Williams talking about associations of common infections with neuroimaging measures of dementia!

New review:
Socioeconomic inequalities in cardiovascular disease: a causal perspective

w/ Liam Wright Nish Chaturvedi, Alun Hughes

Nature Reviews Cardiology Nature Reviews Cardiology

shorturl.at/jBTU3

Centre for Longitudinal Studies MRC LHA @ UCL UCL Social Research Institute (SRI) 🧵...

Last week we heard the news that Alzheimer's drug donanemab had succeeded in phase 3 trials🙌

But what does this mean for people with Alzheimers? Prof John Hardy (UK DRI at UCL) breaks down the results in a Q&A for Daily Mail Online⬇️
UCL Brain Sciences UCL Queen Square Institute of Neurology
buff.ly/3KcJN7u

Tips for analysing observational data:

* If you're studying 'associations', your question is probably causal

* If you have 'confounding factors', your question is definitely causal

* Address confounding with conditioning. Don't create change or ratio variables.

#EpiTwitter

Amazing time networking at the Networking in Neuroscience event –hosted by Alzheimer's Society Alzheimer's Research UK UK Dementia Research Institute Dementias Platform UK

Brilliant first session of #AAIC23 that illustrates the importance of life course studies and intersectionality to study the importance of (early) life adversities on brain health and dementia risk. Including excellent talk by our Eva MRC LHA @ UCL DDisparitiesPIA

“We are working towards real clinical benefit. It’s never been a more exciting time to be a dementia researcher” says Bill Thies award winner and mentor Jonathan Schott ISTAART #AAIC23 MRC LHA @ UCL

Great new study led by Fanny Petermann on lifestyle and dementia UK Biobank

'Association between the AHA Life's Essential 8 score and incident all-cause dementia: a prospective cohort study from UK Biobank'

sciencedirect.com/science/articl…