Excited to announce the Penn Postdoctoral Fellowship in Genetics! We seek to empower and nurture talented early-stage researchers to pursue cutting-edge research in our department.

Learn more here, due Jan. 15.
med.upenn.edu/apps/my/bpp_po…

Very excited to see isoTWAS published today in Nature Genetics!

Big power gains for complex trait mapping via multivariate modeling of isoform-level regulation, particularly in brain.

Fantastic effort led by Arjun Bhattacharya & collab with Bogdan Pasaniuc

rdcu.be/dsrzZ

Our isoTWAS work is out Nature Genetics with the Bogdan Pasaniuc and Michael Gandal labs! A true labor of teamwork, especially from Daniel Vo and Connor Jops with Minsoo Kim Cindy Wen and Jonatan Hervoso. Thanks to reviewers for the thoughtful suggestions!
nature.com/articles/s4158…

Welcome back! If you're looking for a faculty position in the intersection of computational methods and medicine [broadly], consider applying to UCLA CompMed's faculty search! It's a unique department spanning both SoE and SoM. Search is open rank recruit.apo.ucla.edu/JPF08913

Bogdan Pasaniuc Nicholas Mancuso Anshul Kundaje (anshulkundaje@bluesky) @michelnivard Kangcheng Hou Alicia Martin You may ask yourself, what is this Connect thing? dceg.cancer.gov/research/who-w…

Want develop methods while building a rigorous quant foundation? CompMed’s Biomath PhD program is looking for math/stat/bio/CS students. Our new site outlines our three major Focu Areas, Imaging and Biomed Data, Math and Systems Modeling, and Comp Genomics compmed.ucla.edu/phd/overview

Excited for the NHGRI workshop on Advances in Genetic Architecture of Complex Traits Alexander Arguello
genome.gov/event-calendar…

Bonus: you may see some of Sasha Gusev tweets in my slides

x.com/sashagusevpost…

polygenic👏score👏means👏cannot👏be👏compared👏across👏populations

[Figure modified from Ding et al. pubmed.ncbi.nlm.nih.gov/37198491/]

Excited to share that our new multi-group multi-trait #finemapping method MGflashfm, that uses #GWAS summary statistics, has been published online at Nature Communications

Feng Zhou, Opeyemi Soremekun, Tinashe Chikowore, Segun Fatumo, Inês Barroso, Andrew Morris
MRC Biostatistics Unit

rdcu.be/dqK8J

Read more about this new *LDpred2* work, now published in AJHG 🥳

authors.elsevier.com/a/1i372geX6LBo

In the new preprint, we investigate admixed GWAS from a theoretical viewpoint
- What is the estimand?
- How can we improve power?
- What's behind the previously known simulations?
and so on.

(1/n)
medrxiv.org/content/10.110…

Rachel Ungar and I are thrilled to share our paper on the trainee-led course on genetics, ethics, and society that was developed at Stanford: biorxiv.org/content/10.110… (1/9)

I'm writing a molecular perspective on heritability, behavior, (and eventually) race/ancestry, group differences. The idea is to start with what we've learned from genetic data and then work backwards to what we used to know from classical studies.

gusevlab.org/projects/hsq/

Very excited to share this work by Jingyou Rao that is the first in a hopefully very long collaboration with Willow Coyote-Maestas! Hard to believe this started ~ a year ago during lunch at a HHMI NEWS meeting!

x.com/JingyouR/statu…

Meet Rosace, a robust deep mutational scanning analysis tool that incorporates positional information and mean-variance shrinkage. Check it out if you are running DMS experiments or handling DMS data! (1/n)
biorxiv.org/content/10.110…

Congratulations Dr Yi Ding on successfully defending her PhD thesis: 'Uncertainty, portability, and ancestry in polygenic scoring'.

Many thanks to Boutros Lab, Geschwind Lab @ UCLA and Sriram Sankararaman for amazing mentorship!

If you’re an #ashgtrainee looking for a postdoctoral position at #ASHG2023 , happy to meet and chat. Send me an email or DM me!

There's still time to apply! Our TT [open rank] position for a _computational_ geneticist at UCLA closes Oct 31. Apply if you focus on any computational genetics work and ignore the pigeon holing in the application. Feel free to reach out with questions.

recruit.apo.ucla.edu/JPF08482

📢 New AJHG
📰Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics
🧑‍🤝‍🧑Tsz Fung Chan Charleston Chiang Nicholas Mancuso
#HAMSTA
cell.com/ajhg/fulltext/…