Well Manchester, that was different…

Discouraging news today: #MDSsm sabatolimab+azacitidine STIMULUS-MDS2 trial was negative (no OS benefit vs aza alone.) It has been so long since there was good news in HR MDS. If venetoclax+HMA trial is negative will Pharma give up on HR-MDS as too hard?🙁pharmaphorum.com/news/novartis-…

An exciting post-doc opportunity in Dr Batta and Dr. Wiseman's lab! 🩸👇

Learn more 👉 jobs.manchester.ac.uk/Job/JobDetail?…

This week marks a momentous occasion in the life of the Cancer Research UK Manchester Institute - the first research teams from the Institute move into the newest cancer research centre in town.

Look out for updates starting tomorrow on our website

Isn’t it a beauty? The New Paterson building at Christie Hospital, Manchester, U.K.

Clonal hematopoiesis is an expansion of blood stem cell clones caused by mutations in a recurrent set of genes. Our paper on factors mediating expansion of these mutant clones is published today.
nature.com/articles/s4158…

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📣 MEET THE FACULTY OF #ESHCMLMPN2023 !
Join our chairs Claire Harrison Andreas Hochhaus & Ruben Mesa Ruben A. Mesa, MD and all our global experts in Berlin 🇩🇪 on March 3rd!
Register now ➡️ bit.ly/3Rg3ttk
3rd How to Diagnose and Treat: CML/MPN
#ESHCONFERENCES #CMLsm #MPNsm BSH - Haematology

I doubt anyone ever finds a job on twitter but good experience and pay for any aspiring Haematologists ⁦The Christie NHS⁩ bmj.com/careers/job/17…

Please share, opportunity for a prospective PhD student to join my lab and study fascinating condition that is #VEXAS findaphd.com/phds/project/m…

Here is some helpful information for the MPNCo&D delegates as we look forward to welcoming you at the 1st MPNCo&D Congress in just 2 DAYS:
itnewsletter.itnewsletter.co.il/sending/webpag…
The platform is ready & OPEN:mpnlive.cme-congresses.com
Naveen Pemmaraju, MD
Claire Harrison
Ruben A. Mesa, MD

Finally out! #ASH22 #MDSsm attendees, please come and join me in this very interesting session of talks.

I will present how use of #unsupervisedlearning via #ML #multiomics #dataintegration can help us understanding phenotypes and predict drug responses of leukaemia blast cells

Are you interested in studying the role of proteoglycans in inflammation and leukaemia pathogenesis? We have an MRC-funded PhD studentship embedded in a multidisciplinary PI team.
findaphd.com/phds/project/m…
Judi Allen Georges Drupad Division of Cancer Sciences Manchester Cancer Research Centre

Super cool and free 🤩 #mpnsm

The 1st Congress on
Myeloproliferative Neoplasms Controversies and Debates (MPNCo&D) - November 11-12

Chairs Claire Harrison Ruben A. Mesa, MD Naveen Pemmaraju, MD

mpnlive.cme-congresses.com/general-info/

Personally find it sad to see two competing classification systems for myeloid neoplasms. I hope academia and practice can resolve differences amicably. We do what we do for our patients. It is our job to educate and empower them to understand their disease and not confuse them.

What is the risk conferred by my disease? One of the hardest questions to answer in medicine. A on the development of the International Prognostic Scoring System Molecular in MDS published today bit.ly/3aNEU64

✂️🧬GoT-Splice! 🧬✂️
Excited to share new work connecting somatic mosaicism & MDS genotypes to splicing phenotypes in human samples!
Led by the brilliant Federico Gaiti Paulina Chamely Ally Hawkins & Mariela Cortés López team
biorxiv.org/content/10.110…

Good news !
Our article titled 'The longitudinal dynamics and natural
history of clonal haematopoiesis' has just been published onlline. It has been joyous to work with Marga, Jose, Moritz and our collaborators on this exciting story! Thank you all ! nature.com/articles/s4158…

Manumission - Guitarist with Tout-á-Coup Jazz PauleFoster🇪🇺 🐈🌻🌻🇺🇦#FBPE#ProgressveAlliance Ian Lavery MP That is all politics. They promise you the earth and give you feck all. They're all out for themselves. If you haven't learned that by now then I can't help you

How I risk stratify and treat #CMML Clear role for molecular stratification #TET2ASXL1NRAS #NotMDS We owe it our patients to carry out CMML-specific trials and not lump CMML with MDS or MPN. Eric Padron MD Aaron Goodman - “Papa Heme” Sanam Loghavi, MD صنم لغوی 🔬🧬 Naveen Pemmaraju, MD Amer Zeidan MBBS,MHS ‏عامر زيدان

Longer in gestation than an 🐘 but worth the wait: 31 gene molecular IPSS (IPSS-M) for #MDS presented by Elsa Bernard Elli Papaemmanuil, PhD #MDS sm #ASH21 on behalf of MDS Foundation IWG. 6 categories. Complex bioinformatics. 46% of pts restratified from IPSS-R. t-MDS included