Exciting to present about all things polygenic scores & the PGS Catalog to H3ABioNet this afternoon! Thanks GWAS Catalog for organising.

Using polygenic scores to interpret clinical tests - an interesting way to define deviations from a person's normal rather than to a population average.

🎉📣 Latest preprint from the lab: Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology and prediction medrxiv.org/content/10.110…

Led by the exceptional Ruidong Xiang (now head of comp bio at AgriBio Agriculture Victoria)!

📣Latest from the lab: Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities medrxiv.org/content/10.110…

Led by Doug Loesch with Dirk Paul, Abhishek Nag and an excellent team AstraZeneca

Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities medrxiv.org/cgi/content/sh… #medRxiv

Had a really fun night giving two talks all about AI as part of #camfest , thanks to everyone who came and for the insightful questions!

Great position for a methodologist who wants to work on genetic risk prediction - Xilin Jiang is a super-creative scientist and our department is great!

SURVEY ALERT!! Are you generating lists of effector/causal genes based on GWAS? Interested in using other’s lists? Hampered by lack of standards & infrastructure? Together with KP Network we want your input to a new standard: docs.google.com/forms/d/e/1FAI… #gwas #genomics #FAIRdata

Excited to see our GWAS meta-analysis of NMR metabolic biomarkers in 136,000 participants from 33 datasets out in Nature nature.com/articles/s4158… after years of work by many people, esp. Savita Karthikeyan Clare Oliver-Williams Elias Allara Prof M Ala-Korpela Johannes Kettunen & Minna Karjalainen

Interested in a PhD studying multimorbidity using multi-omics data? Studying BHF Cardiovascular Epidemiology Unit at Cambridge VPD Heart & Lung Research Institute with an internship AstraZeneca across the road?

Then this MRC iCASE studentship is for you (due: March 4): jobs.cam.ac.uk/job/45195/!

DMs open for any questions!

Calling all early career researchers interested in polygenic scores, multi-omics and multi-morbidity! Sam Lambert and I are recruiting a Postdoc in Biomedical Data Science, based at the gorgeous VPD Heart & Lung Research Institute BHF Cardiovascular Epidemiology Unit at Cambridge Cambridge Biomedical Campus jobs.cam.ac.uk/job/45465/

Join me at the Cambridge Festival on 19th March to hear about 'Artificial Intelligence, with great power comes great responsibility'! Everyone is welcome, come learn about AI and its relationship with society and ethics :) Cambridge Festival

Great to contribute to the Human Ecosystems @EMBL EMBL-EBI Training course yesterday on behalf of the PGS Catalog with colleagues from GWAS Catalog & Open Targets. Looking forward to seeing some of the other talks on measuring environmental exposures tomorrow!

Day 2 of 'Exploring gene and environmental exposure interactions to understand human health and disease'. Analysing human cohort data with training from GWAS Catalog, Open Targets & calculating Polygenic Risk Scores with Sam Lambert Sam Lambert EMBL-EBI Training

Check out our latest review on polygenic (risk) scores, including the FAIR (Findable, Accessible, Interoperable, and Reusable) use to maximise its clinical utility!

Just out at Genome Medicine: our review on recent advances in polygenic scores: translation, equitability, methods and FAIR tools genomemedicine.biomedcentral.com/articles/10.11…

Well done to the team Ruidong Xiang Sam Lambert Martin Kelemen Yu Xu Helen Parkinson Laura Harris!

An exceptional opportunity to work with both academia and industry experts

Interested in a PhD studying multimorbidity using multi-omics data? Studying BHF Cardiovascular Epidemiology Unit at Cambridge VPD Heart & Lung Research Institute with an internship AstraZeneca across the road?

Then this MRC iCASE studentship is for you (due: March 4): jobs.cam.ac.uk/job/45195/!

DMs open for any questions!