Researchers show epigenetic landscapes control cancer genome instability and susceptibility to PARP inhibitors

For more on how the work presents a
Potential New Treatment for Head and Neck Cancers news.med.miami.edu/new-head-and-n…

Read the full story Genes & Development
➡️tinyurl.com/gd351408

Caeiro, Nakata et al. show that increased H3K27me3 promotes genome instability and susceptibility to PARP inhibitors in H3K36me-deficient head and neck squamous cell carcinoma, highlighting a new therapeutic strategy. Lluis Morey
Read more here:
➡️tinyurl.com/gd351408

We are profoundly grateful that Dr. Ruth Gottesman, Professor Emerita of Pediatrics at Albert Einstein College of Medicine - Official, has made a transformational gift to #MontefioreEinstein —the largest to any medical school in the country—that ensures no student has to pay tuition again. bit.ly/3wvBj7y

🔬 Sylvester's @LluisMorey investigates histone defects in 20% of head & neck cancers, aiming for #ClinicalTrials . This #research could transform long-standing treatment methods and has broader implications for #cancer therapy. #CancerResearch loom.ly/1wXrMa8

Outdated treatments dominate the landscape of head & neck cancer, but a groundbreaking study by @sylvestercancer Lluis Morey reveals a ray of hope. 🌟 Unveiling the molecular secrets & a targeted approach with olaparib and decitabine. #HeadAndNeckCancer
 
bit.ly/49h1TPQ

Very happy to see our new paper published in Genes & Development!

Reduced H3K36me in 20% of HNSCC tumors unlock a critical choice: whether to elevate H3K27me3 or not. Balancing H3K36me and H3K27me is key for therapeutic breakthroughs in H3K36me-deficient cancers shorturl.at/BCGN8

Looking for a motivated postdoctoral fellow to lead research involving #prostatecancer #DNAdamage #epigenetics #therapeutics - Join a vibrant team at Center for Prostate Disease Research, ⁦Uniformed Services University⁩ ⁦Walter Reed National Military Medical Center⁩ ⁦NCI CCR GU Malignancies⁩ careers-hjf.icims.com/jobs/3130/post…

Histone PTM
Acetyl-methyllysine
Marks transcription starts

#ChromatinHaiku
nature.com/articles/s4158…

Thrilled to collaborate with Cigall Kadoch Lluis Morey Scott C Kogan MD Sylvester Comprehensive Cancer Center Daniel Bilbao and Francisco Vega to dissect the role of DPF2 in inflammation & hematopoiesis! Great teamwork!! Thanks to Gloria Na Man for their dedication & expertise!!

Very happy to have the amazing Danny Reinberg as a colleague! Welcome to Miami, Sylvester Comprehensive Cancer Center and University of Miami!

Huge thanks to all, and to Lluis Morey , Arantxa, Xavier Estivill ( #gritelleswinery ) and Natalia for organising this unexpected beautiful surprise, and the great trip together to Priorat!

Still speechless! Past and current lab members came to Barcelona from all-over the globe for the 20th year anniversary of our lab at Centre for Genomic Regulation (CRG) Biomedicina BCN !

Happy to share that I have been promoted to Associate Professor with Tenure. Deepest gratitude to my family, lab members, mentors and friends. 🍾

We are hiring researchers at different stages of career. Please see the ad below Vall d’Hebron Institute of Oncology (VHIO) or our webpage malumbreslab.org

I have openings for a proteomics / mass spectrometry post-doc and bioinformatician (PhD or MSc degree holder), respectively. Each funded for 2 years (extendable). Official ads will follow. Feel free to DM me with a few words on why you want to work with us and a CV. Pls retweet.

🚨📣 Please RT: My lab is looking for a talented postdoc to join our growing team at Sylvester Comprehensive Cancer Center in the beautiful city of Miami.

I will be at the #AACR23 . Interested candidates please reach out to my DM to meet in person in Orlando and chat about this opportunity!