Illuminating cortactin structure and function at #actin filament branches - published by Klemens Rottner and Peter Bieling Max Planck Society in @nature structural & molecular biology
nature.com/articles/s4159…

Illuminating Dark Chemical Matter Using the Cell Painting Assay - published by the Waldmann & Ziegler groups in J Med Chem #chemicalbiology
pubs.acs.org/doi/10.1021/ac…

Wondering about our latest work on #actin filament assembly by #formins 💍? I will present our data at the #MotorsInQuarantine online seminar today at 4pm British time (5pm German time).

Of note, I am actually not a member of the Bieling lab - I work in the Stefan Raunser lab MPI Dortmund.

How Do Molecular Tweezers Bind to Proteins? Lessons from X-ray Crystallography mdpi.com/2749664 #mdpimolecules via Molecules MDPI

Biomolecular #condensates : Are they condensates?
A strategy by the group of Andrea Musacchio to assess the role of liquid-liquid #phaseseparation (LLPS) drivers in cell division reveals poor predictive power of established #LLPS assays
➡️mpi-dortmund.mpg.de/en/news/biomol…

How do you get #proteins out of #DNA ? On #futureday 12 pupils got an insight into our research. They had a lot of fun!
Gestern Girls'Day & #boysday haben 12 SchülerInnen gelernt, wie man aus DNA Proteine erhält. Die Jugendlichen waren begeistert! #sciencemeetsschool

If you are interested in #mitochondria , you could come to #Cologne for your #postdoc !

We are looking for two #postdocs to join us: 1) European Research Council (ERC) funded position in the context of RNA origami, cryoEM, synthetic cells, directed evolution; 2) A position in the excellence cluster 3D Matter Made to Order at the interface of chemistry & biology. Please share and get in touch!

🎨 Featured on the cover of our latest issue:

#CryoEM structure of the #Slo1 potassium channel with the auxiliary γ1 subunit

Read the article here: doi.org/10.1002/1873-3…

Tobias Raisch Stefan Raunser MPI Dortmund

Asymmetric Pd/Organoboron-Catalyzed Site-Selective Carbohydrate Functionalization with Alkoxyallenes Involving Noncovalent Stereocontrol (Charles C. J. Loh and co-workers) MPI Dortmund TU Dortmund #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

Forschende um Stefan Raunser Stefan Raunser und Peter Bieling @peterbieling MPI Dortmund haben erstmals auf molekularer Ebene sichtbar gemacht, wie Formine an die Enden von Aktinfilamenten binden.
science.org/doi/10.1126/sc…

Bild: MPI Dortmund

'One Ring to rule them all': Researchers from the groups of @peterbieling & Stefan Raunser Max Planck Society unveil at the molecular level how ring-like formin proteins promote actin filament growth in cells.

➡️mpi-dortmund.mpg.de/en/news/how-ac…

1/ A new paper from PhD student Marius Hedtfeld tests in vitro phase separation assays as predictors of localisation in cell compartments.

authors.elsevier.com/sd/article/S10…

We explain why homotypic or simple heterotypic LLPS assay are unlikely to predict macromolecular localization...

Curious about the molecular mechanism of #actin elongation by #formins ?
Then check out our latest work in Science Magazine!

This was possible due to outstanding team effort. Big thanks to co-first author Wout Oosterheert, Bieling lab and @intein

MPI Dortmund science.org/doi/10.1126/sc…

Our latest work on #actin assembly is now online Science Magazine!

We show how #formins bind and move with the growing barbed end of F-actin.

Awesome collab. between Stefan Raunser and Bieling labs MPI Dortmund, and big thanks to co-first author Micaela Boiero Sanders

science.org/doi/10.1126/sc…

Chemists in Dortmund have identified the first inhibitors of the cancer-related RNA-modifier METTL16 and have thus taken a first step towards new therapeutic options #RNAmedicine #RNAtherapeutics

➡️mpi-dortmund.mpg.de/news/a-promisi…

My team announced Thermo Fisher's new Hydra Bio Plasma-FIB.

Thanks to Dr. Stefan Raunser / Stefan Raunser from MPI Dortmund for sharing in our excitement! bit.ly/3PYtspV

Cryo-EM structure of Slo1 with the auxiliary γ1 subunit suggests mechanism of depolarization-independent activation.

Redhardt et al. 2023, From Raisch lab Tobias Raisch MPI Dortmund

bioRxiv doi.org/10.1101/2023.1…
peer reviewed by Review Commons eeb.embo.org/doi/10.1101/20….

Job offer for a computational postdoc in a collaboration between me and Sidney Becker at the MPI Dortmund (Max Planck Institute for Molecular Physiology Dortmund). The project is very exciting from both the algorithmic and the molecular perspective! mpg.de/21758900/a-com…

Harnessing Multistep Chalcogen Bonding Activation in the α-Stereoselective Synthesis of Iminoglycosides | Journal of the American Chemical Society -Published by the Loh Group in J. Am. Chem. Soc. #carbohydrates #organicsynthesis #Chemistry pubs.acs.org/doi/10.1021/ja…