🆕Article in press❕

Control Compounds for Preclinical Drug-Induced Liver Injury Assessment: Consensus-driven systematic review by the ProEuroDILI Network

#OpenAccess here👉journal-of-hepatology.eu/article/S0168-…

Spanish DILI Registry
Antonio Segovia Zafra
EASLDHILIconsortium
#LiverTwitter

AGILE 3+ and 4 validated for MASLD & ALD
✅Same overall accuracy (AUC) as LSM
✅Improved classification rate with rule in and -out cut-offs for referral
✅Especially good as 2. line test after FIB4
Journal of Hepatology #LiverTwitter
journal-of-hepatology.eu/article/S0168-…

Fantastic presentation by Archita Desai of Indiana University Gastroenterology and Hepatology at #DDW2024 on
The Cirrhosis Risk Instrument for Stratifying Post-Emergency department mortality ('CRISPE') 👏

redcap.uits.iu.edu/surveys/?s=EFR…

#livertwitter

This is an important paper please take a quick read you will learn a lot regarding screen failure rates in Nash trials and what to do about it AASLD Digestive Disease Week EASLnews

Active intervention did worse than standard of care if the results were to reflect the aim of the study.

Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis

Full text here👉journal-of-hepatology.eu/article/S0168-…

#LiverTwitter

Ran into this poster @ddw2024
Social media based research on #DILI - Scraping Reddit for self reported -selective #androgen receptor modulator- a.k.a #SARM DILI.
Naga Chalasani Raj VuppaLanchi Robert Fontana Lily Dara Gina Choi sidbarritt4 David Kleiner

Dr.Loomba talking about who needs to be treated and identifying treatment responders to Rezdiffra. MRI-PDFF is best biomarker for treatment response

Samer giving his state of art lecture on MASH therapeutics Indiana University Gastroenterology and Hepatology Mazen Noureddin, MD, MHSc Mohammad Al-Haddad, FASGE,FACG, AGAF Naim Alkhouri

On Saturday, if you are not heading to the American Gastroenterological Association (AGA) post-grad course (which we highly recommend but is associated with a $50-75 fee), be sure to check out these sessions! The academic debate is sure to be a lot of fun!

Liver injury after gene therapy by Dr.Raj Reddy LiverTox Lily Dara

Liver at nexus of inflammation and cell death in Cancer Immunotherapy Lily Dara ‘s state of art update on the topic LiverTox

jonnysexton teaching us about the challenges and limitations of predicting #DILI in vitro and how patient-derived organoids can overcome many of these at the #IQDILI meeting. Tangential flow and MPS models increase physiologic relevance. Beautiful images and cutting edge science

A day of all things #HEPATOTOXICITY ! DILIN investigators at the IQDILI meeting discussing classic idiosyncratic #DILI and our experience, #HLA , #genetics , #HDS , #HILI and more Robert Fontana Lily Dara Raj VuppaLanchi Gina Choi

FLLC injury 24% hospitalization rate with no death or liver transplant but 6% underwent cholecystectomy. Non protein amino acids (NPAA), L-Baikiain causes depletion of glutathione and hepatic injury LiverTox Lily Dara

Kinase inhibitors and biological dominate the new drug approvals LiverTox Lily Dara

Wishing you everything and more of what you are seeking in your pilgrimage

My dear friend Raj VuppaLanchi sharing valuable insights on PBC:
1. Role of liver stiffness on VCTE in prognosis
2. Deep response
3. New drugs Gilead Sciences Ipsen . Turkish Liver Meeting Sonal Kumar, MD MPH Cynthia Levy, MD PBCers Organization

Here in Rize, Turkey for 15th annual Hepatology Congress - patients with HILI may not report unless persistently questioned Lily Dara LiverTox

Dr.Dara is standing taller than Dr.Bonkovsky - “definite”ly unintentional but “highly likely” to have happened from “probable” encouragement from “possible” colleagues but otherwise “unlikely” to have occurred Lily Dara