#TumorBoardTuesday Rachel Riechelmann Integrity CE, LLC 👨🏽🏫Mini Tweetorial 2👨🏽🏫
✅PPGL are molecularly classified into 3 types: 1⃣Pseudohypoxic (HIF, VHL, SDHx alterations)
2⃣kinase signaling (RET alterations)
3⃣Wnt-altered: They typically have low TMB and rare actionable mutations
doi:10.1038/s41467-023-36769-6
Delighted to share our new work in Nature Cancer in collaboration with Schofield Group led by Hannah Lawson & James Holt-Martyn. We found that HIF hydroxylases are potent therapeutic targets in AML. The ICR. nature.com/articles/s4301…. 1/4