part 2 #MCAS
#MedicalEducation #MERC #MastCellActivation #MECFS #pwME #fatigue #LongCOVID #anaphylaxis #Tryptase #Histamine #Interleukins #Leukotrienes #Arrhythmia #Headache #AbdominalPain #Brainfog #Diarrhea #Hypotension #Vertigo #Flushing #Edema #Hives #Inflammation #Asthma

What happens when you cross two of natures greatest compounds?

You get (Black seed honey)

Black seed oil x Raw honey

// Anti-inflammatory \\

1) Black seed oil (Thymoquinone)

- Inhibits the production activity of pro-inflammatory cytokines and enzymes (such as interleukins

My physiology professor explaining leukopoeisis and the interleukins related with each step.

My brain-

Psoriasis as a risk factor for stroke.
Ps is a Chronic inflammatory skin condition that is Pro-atherogenic.
Ps triggers an immune response with activation of T cells, myeloid cells, and platelets.
Ps increases TNF-alpha, and interleukins [ IL-23, IL-17, and IL-6] which are

The next one in this ABCs of Immunology: I is for interleukins.
Do you have a favorite #interleukin ?
#CellCartoons #SciArt #ScienceArt #MedicalArt #sciencecommunication #sciencecomics #ABCs #iloveimmunology
#immunology

🧪 With a track record in enzyme production encompassing DNA & RNA polymerases, ligases, terminal transferases, inhibitors, interleukins, growth factors, CAZY, IVT & IVD enzymes and more, we're your trusted partner for preclinical and clinical phases.

🔗 53biologics.com

$CRVS 3Q Conference Call.... some nice discussion of Ciforadenant exceeding expectations for deep response for first 8 patients and more $CRVS focus ITKi on interleukins and looking for partnering on immune Th2 and Th17 inhibition program.

Explore Interleukins: Key cytokines shaping the immune system. From IL-6 to IL-32, these proteins play vital roles in immune response and cell differentiation. Dive into a world of research tools—ELISA kits, recombinant proteins, and antibodies—to unravel their mysteries.

⬆️ interleukins (IL)-1α, 1β, 2, 4, 5, 6, 7, 8, 9, 10, 13, 15, 17F, 22, and 27 and ⬇️ IL-3 levels are seen in patients with JIA, suggesting that a combination therapy aimed at inhibiting both nonspecific and activating B-cells ILs would be more effective

🔗doi.org/10.3390/biomed…

Inflammation is controlled by a group of proteins called Interleukins.

But most people don't know what they do.

Here's the full list and their roles in inflammation;

$CRVS New slide presentation from Nov 1st.

Highlighting how ITKi by #soquelitinib can stop both Th2 and Th17 cells from forming upstream and affect numerous interleukins downstream. This is completely novel MOA and approach to treating these #autoimmune diseases.

Targeting Interleukins to Improve Treatment Outcomes in Atopic Dermatitis

$CRVS ITKi MOA inhibits production of IL-17, IL-23 upstream and is potentially superior to current #antibody therapies.

Antibodies have a 1:1 or 1:2 ratio w/ interleukins they bind, whereas #soquelitinib stops #Th17 , thus inhibiting thousands or even millions of ILs from forming

Kicking off #CCCongress24 IBD A-Z with Jessica R Allegretti discussing #interleukins & how/when to use…

#CCCongress24 #IBDResearch #IBDTreatments #IBDEducation

Coming soon...
Cansure toothpaste MRP: ₹199/- Contact us to become a distributor or a dealership. Mail us at [email protected].
Oral cancer can be triggered by increased levels of TNF-alpha, IL-8, IL-6, and interleukins.

¿Colchicine will be used in secondary prevention of ischemic heart disease, for patients with high-sensitivity C-reactive protein ≥ 2 mg/L.
Or we will manage other inflammatory biomarkers. Interleukins?

I posted on this a few weeks ago, $ACRS not a selective ITKi see below.

Selectivity of $CRVS #ITK inhibitor #soquelitinib is KEY and makes $CRVS the only true ITKi platform.

#Soquelitinib inhibits CD4+ from becoming #Th2 and #Th17 and thus lowers whole groups of interleukins.

$CRVS updated slide presentation:
(1) ITK inhibition w/ #soquelitinib stops interleukins IL4, 5, 6, 13 (Th2) and stops IL17, 21, 22 (Th17)
(2) potential to be treatment w/ other Tcell therapies, ie CAR-T, etc
(3) three new studies to begin 1H24! Data 4Q23

corvuspharma.gcs-web.com/static-files/7…

Aladdin's Interleukin Adventure: Unraveling the Language of Immune Response
🔬✨Explore the world of immune system signaling with Aladdin Biochemical's Interleukins product line. 🌟💡 #Interleukins #Immunology #ScientificDiscovery #AladdinScientific
aladdinsci.com

🔴Great talk by Miguel Regueiro ; on Optimizing the use of interleukins and integrins in IBD Rx.👇🏼
#gitwitter
#Teaching
#SGA
#IBDMASTERCLASS2023