Finerenone in patients with chronic kidney disease & type 2 diabetes:Pharmacokinetics & pharmacodynamics
👉Insights based on FIGARO-DKD & FIDELIO-DKD
dom-pubs.onlinelibrary.wiley.com/doi/10.1111/do…
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Correct answer = A.
Vd = dose/C = 2000 mg/28.5 mg/L = 70.1 L. Because the patient is 70 kg, the apparent volume of distribution in L/kg will be approximately
1 L/kg (70.1 L/70 kg).
The calculation is also attached as below:
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Today we announced the initiation of our Phase 2 study of ALTO-203 in patients with #MajorDepressiveDisorder & elevated #anhedonia . We look forward to further evaluating the pharmacodynamics, pharmacokinetics, and tolerability of ALTO-203. Read more: brnw.ch/21wIt52
Many factors impacting antifungal drug pharmacokinetics in these patients #ECCMID2024 #ESCMIDGlobal2024