Limitations in susceptibility testing - one of several factors that highlights the importance of antibiotic #DoseOptimization asm.org/index.php/mbio…

🆕in #JAC 'Pragmatic options for #doseOptimization of ceftazidime/avibactam with aztreonam in complex patients'

academic.oup.com/jac/advance-ar…

Experts echo goals similar to those of #PCDI (⁦The Right Dose) ⁦Friends of Cancer Research⁩ ⁩ #FriendsAM22 #doseoptimization #MoreIsNotBetter #PatientCentricMedicine #ProjectOptimus ⁦FDA Oncology⁩ #PROs #MTDisTheOldParadigm #bcsm #Cancer #ClinicalTrials link.springer.com/article/10.100…

'Radiology Today: Children's Hospital #DoseOptimization
bit.ly/1rGmTmB' protocols can be optimized based on the diagnostics - #mim2021

Key approach for #DoseOptimization Imaging procedure in children #CAHD #ImageGently bit.ly/2uOOzjx

Nothing like a peer reviewed paper led by a fierce group of patient advocates highlighting the need for improved dosing in oncology to start your Sunday. 👏🏼👏🏼👏🏼 #doseoptimization

This report by AgencyIQ on the FDA's dose optimization guidance for oncology products provides insights into the contrasting viewpoints of regulators, researchers, patients, and industry.

Read the full article here: ow.ly/HZZu50OzHHW

#FDAguidance #DoseOptimization

Interesting that 40%+ in the CREDIBLE study received reduced doses of cefiderocol due to renal impairment. When mortality was attributed to baseline GN pathogen, ~2/3 received reduced doses. Opportunity for #DoseOptimization ?

On the issue of cefiderocol for cUTI there were 14 “yes” votes and 2 “no” votes from the advisory committee. Some calls for additional data, and labeling warnings about increased mortality seen in the CREDIBLE study. FDA Drug Information SIDP #IDtwitter

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The #FDA granted accelerated approval for the first drug approved to treat HER2-mutant non-small cell lung cancer, following a blinded, randomized #DoseOptimization study designed using #ProjectOptimus guidelines: bit.ly/3QYnJi5 #Oncology #DrugDevelopment

This important thread 👇🏻👇🏻

#bcsm
#doseoptimization

Modern middle-mile logistics strategies are critical to your business.

You need to optimize the entire journey if you want the lowest costs and the happiest customers.

Physicians lower doses to deal with side effects and sometimes even start lower than the approval. Another great set of work supporting a need for better dose optimization (complements the.right.dose’s findings!) - IMO #doseoptimization should be BEFORE approval.

Yes and increasing knowledge among the oncology community to be more aware of these data and paradigm shifts in dosing of targeted therapies. The Right Dose was a movement started by patients to do this.

Thanks to AnneL, founder the.right.dose, & all members, plus our brilliant Medical Advisory Board, for moving the needle forward on imp of #doseoptimization of targeted tx for pts w/ #metastaticbreastcancer . Out w/ MTD paradigm, in w/ personalized Med approach.
🎯🧵👇🏻
#bcsm

We aim to develop better treatments that can make a real impact in people’s lives. Learn more about us here: bit.ly/3jNmovI

$MBXR #STSLungMets #Sarcoma #AcuteMyeloidLeukemia #Oncology

#regulatoryscience #regulatorystrategy #drugdevelopment #doseoptimization #diversity #expandedaccess #pediatriccancer #expeditedprograms #combinationtherapy #cancer #oncology #fda

For some people living with HER2+ breast cancer, this is encouraging news! Treatment-related toxicities can significantly impair QoL, & de-escalation offers potential imp through patient-centered medicine approach.
#DoseOptimization
#PersonalizedMedicine
#BreastCancer
#bcsm

De-Escalation Has Lasting Benefits for HER2+ Breast Cancers medscape.com/viewarticle/99… - thanks to @medscape for featuring our long-term analysis of the APT trial Sara Tolaney Dana-Farber’s Breast Oncology Center

Being exposed to low-dose ionizing radiation is associated with an increase in pediatric patients' risk of developing cancer, according to a new study published in JAMA Network Open.
#dosimeter #doseoptimization bit.ly/35hFdhe

Looking for ALARA best practice ideas and decreasing dose in your patients and staff? West Physics' own Richard R. Miguel will be a panelist on the Imaging Technology News (ITN) Editorial Roundtable Series! Registration at lnkd.in/ginSHaNP
#medicalphysics #doseoptimization

About half oncologists who responded to ASCO's survey agreed that patients should start at a lower than the approved dose, and increase if well-tolerated. #doseoptimization #startlowgoslow ascopubs.org/doi/10.1200/OP…

West Physics' own Richard R. Miguel, M.S., DABR will be one of 3 industry experts discussing the management of fluoroscopy radiation dose. Register for free at workcast.com/register?cpak=…

#medical physics #experts #learn #healthcare #medical #doseoptimization #fluoroscopy

Attending #ASHP20 ? Kristi Kuper highlights exciting #doseoptimization presentations that you shouldn't miss in our latest blog.
loom.ly/QPgBxB4

📢New paper from the.right.dose=Important. An overwhelming majority of the responding oncologists - 97% - would be willing to discuss individualized dosing with patients based upon the patient's unique attributes #cancer #bcsm #patientExperience link.springer.com/epdf/10.1007/s…

We have recently collaborated with regional experts, Prof Jayesh Desai, Prof Do-Youn Oh and Prof Pan Hongming, for an in-depth discussion on FDA's #ProjectOptimus . Watch the interview as we delve into #earlyphase #oncology development & #doseoptimization : bit.ly/43qIY2F

Todd McCarty 💊🐉👨‍⚕️ Gotta love #doseoptimization !