An #astrocyte BMAL1-BAG3 axis protects against alpha-synuclein & #tau pathology | The #autophagy chaperone #Bag3 is a #parkinsons GWAS hit & prevents protein aggregation | by an amazing team lead by Pat Sheehan Albert (Gus) Davis MusiekLab via Neuron sciencedirect.com/science/articl…
🎉 Kao Lab celebrating Dr. Paul Sampognaro and Dr. Molly Hodul for their published research paper! 📚🌟🎉
Learn more about how mutations in α-synuclein, TDP-43, and tau hinder lysosomal degradation, extending their half-life: …arneurodegeneration.biomedcentral.com/articles/10.11…
#lysosomes #Celebration
Great to see another successful collaboration published. #αsynuclein ubiquitination mediates endosomal trafficking, out now in
Science Advances. Congrats to George Tofaris, Roman Fischer, and everyone else involved!
Check it out here:
science.org/doi/10.1126/sc…
Featuring another terrific session at the FASEB #protein #Aggregation Conference. If you are curious on the architecture of toxic #synuclein #oligomers and how they transition to #amyloid fibrils Don’t forget to check out our poster P29!