Rebecca Nisbet
@NisbetADlab
Head of Antibody Therapeutics Lab | The Florey Institute of Neuroscience | Striving for a cure for Alzheimer's | Dedicated to mentoring ECRs
ID:1461183182288474116
18-11-2021 04:03:30
74 Tweets
202 Followers
147 Following
Elsevier revenue at 2.9 billion pounds, profit margin nearing 40% - the #OpenAccess model is an obscene fraud that wastes charity and public money. Finally some action by scientists though -
theguardian.com/science/2023/m…
It was an absolute pleasure to write a perspective on the amazing work from the lab of William McEwan published in Science that will hopefully lead to the development of better tau antibody therapies for the treatment of AD
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
This week in Science Magazine: Aamir Mukadam, William McEwan, &al. treat mouse models of #tau pathology w/ α-tau #antibodies by engaging cytosolic Ab receptor #TRIM21 !
bit.ly/Sci_abn1366
w/ Perspective by Rebecca Nisbet:
bit.ly/Sci_adg9800
#neurodegeneration #immunotherapy
Do anti-amyloid drugs protect the Alzheimer's brain? Francesca Alves Pav Kalinowski & I performed a meta-analysis of all clinical trials (8k-10k subjects) and showed that anti-amyloid drugs constantly accelerate brain atrophy, but the area of the brain affected depends on drug class
Time to put down the tools! Another Honours year University of Melbourne coming to an end! Congratulations Alayna Carmina Caruso on a fantastic year in the lab. Good luck with the thesis writing and see you back here for a PhD!
A professor once told me to, when editing, re-read your work separately for every editing 'theme'. Compartmentalising editing should make it more productive, rather than endlessly reviewing & finding different issues every time. Here's themes I cover when editing:
1/2 PhD Voice - Independently Run
Happy #nationalscienceweek ! To celebrate we have been doing exothermic and endothermic reactions at home with yeast, vinegar, baking soda and hydrogen peroxide.
Our paper on gender disparities in career outcomes for dementia researchers is out!
However, in this thread let me focus not on the results but on what Research at ARUK has done *this past year alone* to address the issues we found in this analysis.
amrcopenresearch.org/articles/4-18/…
Our new paper in JCR is a great example of why it’s so hard to treat neurological diseases. Getting drugs in the brain is just half the challenge- Ensuring they reach their target is a whole other hurdle! Rinie Bajracharya Juergen Goetz Queensland Brain Institute, UQ The Florey
Very excited to find out that our work The Florey to develop next generation immunotherapies for the treatment of AD has been funded by the Alzheimer's Association. Thank you Alzheimer's Association! Let’s #ENDALZ ! Laura Vella