Paper alert:

Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer's disease trial - Molina‐Henry - Alzheimer's & Dementia #ENDALZ
alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

Join⭐️mcisymposium.org, Fri 19, 9:30am & applaud Nicholas Ashton,Breton Asken,Rosie Curiel, Larry Honig, Thomas K. Karikari, PhD,Firoza Lussier,Niklas Mattsson-Carlgren, RonPetersenJr,Gil Rabinovici, Vijay Ramanan, MD PhD,Suzanne E Schindler,Steve Salloway, Steven DeKosky,Reisa Sperling,Madhav Thambisetty, et al!

HAI-ers, join the FREE mcisymposium.org tomorrow (Fri, Apr 19, 9:30am ET) to learn/applaud our esteemed [HAI] stars: Breton Asken, Thomas K. Karikari, PhD, Firoza Lussier, Niklas Mattsson-Carlgren, Ron Petersen, M.D. , Gil Rabinovici, Steve Salloway, Suzanne E Schindler, Steven DeKosky, Reisa Sperling+more!

Out now in The Lancet Neurology A comparison of tau PET pathology in Down Syndrome (DS) and Autosomal Dominant Alzheimer Disease (ADAD).
thelancet.com/journals/laneu…

The #lecanemab clinic at #WashUMed is one of the largest and began infusions in August 2023. Lecanemab is a FDA approved treatment which can slow disease progression for those with early stage #Alzheimers .

Learn more about lecanemab: medicine.wustl.edu/news/what-to-k…

A new era is dawning for Alzheimer's disease, one in which we could delay or even prevent the disease from developing. [Sponsored by Davos Alzheimer’s Collaborative]

trib.al/jstot7F

The World Health Organization (WHO) is seeking feedback on the preferred characteristics of AD blood tests. #ENDALZ

who.int/news-room/arti…

Congrats to Prof. Tammie Benzinger, MD, PhD, who was honored with the AWN Mentor Award from the Washington U. Med Academic Women's Network. As a mentor for multiple training programs, Dr. Benzinger is crucial to training the next generation of imaging scientists and radiologists.

And now, we have the research briefing out, for those interested in a more detailed and personal description of the paper.
nature.com/articles/s4358…

Discover our lineup of keynote speakers for #CTAD24 ! Dive into cutting-edge research and insights at the forefront of Alzheimer's treatment and care.

ctad-alzheimer.com/keynotes

Former ⁦WUSTL Sleep⁩ fellow ⁦Rutwik Patel, DO⁩ is first author on this paper led by ⁦Eric Landsness⁩! Thank you for highlighting ⁦CNN⁩! ⁦Washington University Department of Neurology⁩ ⁦Center On Biological Rhythms And Sleep⁩ cnn.com/2024/04/04/hea…

New method to evaluate early tau spatial spread in Alzheimer disease, congrats to Stephanie Doering on this 1st author paper in Lancet eBioMedicine! thelancet.com/journals/ebiom… Mallinckrodt Institute of Radiology MIRNeuroradiology Knight ADRC

🚨 Excited to present our RUSH Alzheimer's Disease Center work combining MARS & Medicare data: Everyday discrimination and more hospitalizations in older Black adults, led by Brittney Lange-Maia, PhD, MPH as well as Ana Capuano Fran Grodstein Lisa L. Barnes, PhD (Barnes Young) ! Gerontological Society of America (GSA) @oxfordjournals academic.oup.com/biomedgerontol…

A huge shout out to Stephanie Doering for her first 1st author paper in the Benzinger Neuroimaging Laboratory. Stephanie compared the utility of quantifying the spread of tau PET relative to the intensity of tau accumulation. Great job Steph! Washington U. DBBS Knight ADRC
thelancet.com/journals/ebiom…

kate foley, phd and I just published this review in Stroke outlining promising plasma biomarkers for small vessel disease - check it out!

In this paper led by my grad student Przemek in Gothenburg, we describe p-tau212 as a new blood biomarker for Alzheimer’s disease 🩸.
- Plasma p-tau212 had same accuracies as p-tau217.
- P-tau212 antibody stained tangle structures in postmortem brains.

nature.com/articles/s4146…

Beyond excited and proud to be invited to give a keynote at #CTAD2024 and in such fantastic company. This meeting is the place to be for cutting edge #dementia #clinicaltrials research - don't miss it! UCL ION NIHR UCLH Biomedical Research Centre

The clinical utility of Alzheimer disease blood tests is strongly related to their accuracy. Lower accuracy blood tests will simply not be helpful. #ENDALZ

Lower Accuracy Alzheimer Disease Blood Tests Will Never Be “Ready for Prime Time” | Neurology neurology.org/doi/full/10.12…

Online now! Salvadó et al., develop and validate a CSF-based staging model for sporadic #Alzheimer , which accurately reflects biomarker and clinical changes, enhancing diagnostic and prognostic assessments of participants for clinical setting and trials. doi.org/10.1038/s43587…

Thank you Alzforum for this writeup about our recent work on TREM1 in aging and Alzheimer's disease:

'TREM1 Muddles Myeloid Cell Metabolism and Memory in Old Mice'