Friday #cellfie . Dotting the i’s for the next Wray Lab manuscript!

APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease dlvr.it/T4Lzx5 #genetherapy #celltherapy

We are on the lookout for new players! As you will see in today’s article in the Oxford mail, we are offering free membership and free match fees to all existing and new players for the coming season. Get in touch if you are interested!

oxfordmail.co.uk/sport/24211136…

#StemCellTuebingen . Just touched down in Germany. Really looking forward to the meeting. If you’re going to be there too, please come say hi!!! 👋

Countdown to 'Stem Cells in Neuroscience' (stemcelltuebingen.com) Get ready to be excited, connected and inspired by brilliant scientists. See you in Tübingen on Monday!
#StemCellTuebingen DZNE Research Center Hertie-Institut für klinische Hirnforschung (HIH) TübingenNeuroCampus

Reviewers’ comments received whilst in the pub. To open or not to open…

The UK Glia Network is live - FOLLOW UK Glia Network and REPOST 😊 We will be meeting in person in September 2024 – stay tuned for more details!!
British Neuroscience Association , Cam Neuroscience , Cambridge University , London Glia Community , Edinburgh Neuroscience , The University of Edinburgh , The University of Sheffield , University of Bristol

Excited to announce upcoming one day symposium followed by 4 day course in how to model and manipulate IPSCs aimed at ECRs. PLEASE RT!
jax.org/education-and-…

There is a really interesting conference this April in Spain on both autosomal dominant AD and Down Syndrome supported by the Down Syndrome and Alzheimer's Disease PIA and ISTAART. Put it on your radar if you are interested in genetic forms of #Alzheimer
dsad-adad.com

Thank you to PacBio for the invitation to speak last month and this awesome Revio model. Took us a while, but let the home long read sequencing begin!!

So stoked to be sharing this! New proteomics map of human subcellular architecture. CRISPR + organelle IP mass spec at scale. Check out pre-print biorxiv.org/content/10.110… and organelles.czbiohub.org. 🙌 to fantastic team Chan Zuckerberg Biohub Network SF & collabs! 1/2

Quantifying the performance of 614 #antibodies for 65 human proteins demonstrates the scale of the antibody liability issue.
Good news? we CAN help identify a successful antibody for your protein of interest.
➡️doi.org/10.7554/eLife.…
#antibodyvalidation #reproducibility

#NewProfilePic

Brilliant list with some amazing scientists.

We are organising a microglia & MS meeting, Feb 15-16 2024 in Groningen. For information, speakers and registration see microglia2024.com
Hope to see you next Feb!

It is not fresh to know that γ-secretases process APP to generate Aβ. But what do they cut in microglia? Why do they cut so many proteins in the meantime? Our paper just published in Molecular Cell provides new insights on these topics. Check it out: cell.com/molecular-cell…

Very exciting opportunity for a postdoc in Gothenburg. Awesome lab and awesome project!👇

eur01.safelinks.protection.outlook.com/?url=https%3A%…

We are hiring! Senior research fellow position available working with us & Sarah Tabrizi's group to use patient derived organoids to assess toxicity, uptake, trafficking and target engagement of novel Nucleic Acid Therapy (NAT) compounds:

ucl.ac.uk/work-at-ucl/se…

Stem cells meets Neuroscience. Registration is now open for the 'Stem Cells in Neuroscience' meeting 11-13 March 2024 in Tuebingen. Join us for awesome keynotes, engaging poster sessions and career workshops TübingenNeuroCampus DZNE Research Center

Come and work with us!
We are recruiting two positions UK Dementia Research Institute in Cambridge on a drug discovery collaboration between Drug Discovery Unit and Cambridge University for Alzheimer's disease.
- Postdoc jobs.cam.ac.uk/job/43160/
- RA jobs.cam.ac.uk/job/43158/
#AcademicJobs #research #DementiaResearch