'Submission' in June sounds good, but indicates further delay! When is publication? Many questions/suggestions arise. Here's one… Will you urge #Mirocals Consortium @NigelLeigh3 to publish PREPRINT now so clinicians can assess results & save time? Will you King's MND Centre Neuroscience Institute?

Not long after I was diagnosed with #MND in 2018, I joined a clinical trial called MIROCALS
In Dec 2022 the initial trial data showed a significant slowing of progression in trial participants who received low dose Interleukin 2.
The MND community are now demanding further action

A drug locked away from MotorNeuroneDisease yet readily available from NHS for other conditions & shown provisionally to delay death in #MND . Confirmation is needed but why is #Mirocals Trial Consortium developing a drug different from the trial drug? united2endmnd.org/2024/05/14/mir… Neuroscience Institute

We'd like to acknowledge the deep frustration within the #MND community around the ongoing wait for the publication of the MIROCALS trial results.

We share that frustration.

Read our MIROCALS statement here: mndassoc.org/mirocalsstatem…

Yesterday we brought together leading MND minds at our Scientific Advisory meeting. Amongst many other topics, we discussed the latest update on publication of data from the MIROCALS trial. Find out more 👇
myname5doddie.co.uk/whats-on/artic…

#Mirocals
#attackmnd

⁦Tanya Curry⁩ and 6 members of her ⁦MND Association⁩ management team are handsomely remunerated, so perhaps they could demonstrate why and fight harder for the community that funds them. The silence is deafening. We just want the data. #mirocals

Patients United2EndMND nigel leigh King's MND Centre Neuroscience Institute Preprint, if the #mirocals consortium chooses, can happen IMMEDIATELY on submission to journal. Submission in June without preprint will typically mean published in September/october! Is that acceptable #mnd #also community?
#united2endmnd

Please take a look at this open letter addressing the very important issue regarding the lack of information around the results and data from the Mirocals trial. The reason it is so important is that we are being denied access to a potentially effective treatment, Interleukin 2.

Last week Patients United2EndMND supporters Darby Rimmer MND Foundation Steph Houghton MBE Rob Burrow CBE Geoff Burrow Ed Slater & Jo, Marcus & Louise Stewart asked vital questions of 4 UK #Mirocals Consortium members. Pls go to united2endmnd.org/support-miroca… to read & sign to support our plea for transparency

Please add your signature to letter to Mirocals Consortium members from our high profile patient colleagues here united2endmnd.org/2024/04/30/wou… Clear answers should help speed access to life prolonging drug for MotorNeuroneDisease if +ve provisional results are confirmed. Please share.

If #Mirocals trial results are +ve Patients United2EndMND want to see #MND clinicians use fastest routes to access low-dose #Proleukin . We believe terminating #Iltoo contract now & finding new partner will help! See united2endmnd.org/2024/05/10/pat… MummywithMND Geoff Burrow Darby Rimmer MND Foundation

We believe that if results of the #MIROCALS trial are as positive as we all hope, everyone who is eligible should have access to the drug without delay.

People with MND don't have time to wait & we'll continue to push hard for progress.

Full statement: myname5doddie.co.uk/whats-on/artic…

We share the frustration within the #MND community around the wait for the publication of the MIROCALS trial results.

Read our latest statement below.

People living with MND don't have time to wait.

Today, alongside MND Association & MND Scotland, we have written joint letters to both regulators and ILTOO pharma regarding the MIROCALS trial.

Full update 👇
myname5doddie.co.uk/whats-on/artic…

16 months #mirocals . 16 months of uncertainty and lack of transparency. Inexcusable

My MIROCALS / IL2 UPDATE‼️
Today I was told that despite the fact I took part in the MIROCALS clinical trial & ILTOO want to supply the potentially groundbreaking #MND drug. An NHS committee have decided that as the trial was in Glasgow & I live 150 miles away,
I CAN’T GET IT 😡

As we await final results from #mirocals trial for low dose il2 for #mnd #als - today we ask question 'Have the Mirocals consortium chosen the right path to getting to patients in the event of positive results?' Spoiler alert, we fear not.

#united2endmnd

united2endmnd.org/2024/05/14/mir…

Some positive news to counter the recent understandably negative sentiments towards the MND Association @Mirocals & @IltooPharma. The news of a mechanism for early access to IL-2 is very encouraging.

Filipe Morais thank you so much. The #mnd community deserves to know the results. Positive or negative #mirocals