✨Preprint to check out✨
tinyurl.com/CRTFTiles
How do our genes turn on⬆️and off⬇️?
The regions within proteins that do this are called effector domains (EDs), and when I began this project, we were missing ED annotations for more than half of the #TranscriptionFactors .
She did it! Congrats @RNameki #phd #ovariancancer #generegulation #transcriptionfactors #research #pax8
Sharing my discoveries with amazing scientists BBCB Graduate Group retreat. #transcriptionfactors #chromatin #nucleosomes #pioneerTFs
Investigating #transcriptionfactors ( #TF ) controlling #floralorgan development to understand the mechanism of #wheat #cleistogamy and #genetics of wheat flower development and evolution. This research will help to untangle #molecular intricacies of floral TF functions. #MADSbox
Sterol regulatory element-binding proteins (SREBPs) are #transcriptionFactors that bind to the #sterol regulatory element #DNA sequence TCACNCCAC. Mammalian SREBPs are encoded by the genes #SREBF1 and #SREBF2 . SREBPs belong to the #basichelixloophelix #leucineZipper class of tran
Pre-print is out…👍🏻👇🏻 Screening of Aspergillus fumigatus transcription factors reveal distinct cohorts of regulators moderate epithelial damage during infection #aspergillus #hostdamage #fungus #lung #screening #transcriptionfactors #epithelialcells
Let's degrade some #TranscriptionFactors ! Great to see our #TRAFTAC story by Kusal Samarasinghe et al in print at CellChemicalBiology #PROTACs #targetedproteindegradation Transcription Factors Chordoma Foundation Brachyury (TBXT)
authors.elsevier.com/a/1ctE58jWWJlv…
Benchmarking tools for transcription factor prioritization. #TranscriptionFactors #Benchmarking bioRxiv
biorxiv.org/content/10.110…
Researchers identify gene responsible for cellular aging
#Aging #MesenchymalStemCells #Reprogramming #TranscriptionFactors #CellSignaling #MSCs
…cellsjournals.onlinelibrary.wiley.com/doi/abs/10.100…
bit.ly/3qezxQz
Great experience with the poster presentation today at the #SBSannualevent2020 #aspergillus #transcriptionfactors
Our study finding that the evolution of #transcriptionfactors (TFs) is shaped by levels of transcription factor activity, expression, and existing connectivity is out now in PLOS Biology !! Read on below for an overview of our study (1/16).
journals.plos.org/plosbiology/ar…
Join us! For the next Variant Effects Seminar Series
🗓️📌Tues Apr 5th
⏲️3 pm PDT (UTC+1)
Talks by: Shawn Fayer ( #geneticcounselor #BRCA1 , #functionalgenomics ) and
Marty Yang ( #geneticvariation #cisregulatory #transcriptionfactors )
Details > varianteffect.org/seminar-series
Was great speaking at the Discovery on Target #BostonDOT23 yesterday! #chromatin #drugdiscovery #epigenetics #transcriptionfactors #cancer
Warm welcome to all participants & speakers! We are ready! #ICGEBWorkshop #Transcriptionfactors #cancertherapy #ICGEBCapeTown
Unlocking the secrets of MYB genes in plants! Discover how an automatic annotation pipeline revolutionizes the identification and functional annotation of MYB gene family members. Fascinating insights await: doi.org/10.1186/s12864… #PlantGenetics #TranscriptionFactors
Expression of key #developmental #transcriptionfactors is usually regulated by complex regulatory regions containing cluster of #enhancers , often organized in a #superenhancer . Analyzing the evo of such region we have made interesting discoveries 1/n biorxiv.org/content/10.110…
Exploring #TranscriptionFactors : How these master regulators influence cancer's newest hallmarks and offer novel therapeutic avenues.
Read the review by RCSI’s Professor Maria Morgan and Dr Sudipto Das from RCSI School of Pharmacy and Biomolecular Sciences.
➡️ doi.org/10.1016/j.semc…
#RCSIdiscover
GATA6 regulates aging of human mesenchymal stem/stromal cells
#aging #cellsignaling #mesenchymal #stemcells #reprogramming #transcriptionfactors
bit.ly/2Lm9x6a
Knowing how and where #TranscriptionFactors bind to the #genome is crucial for understanding how they control #GeneExpression . This #FreeReview looks at how human TFs are identified and the ways they interact with DNA sequences. --> bit.ly/2nQ4SKN
