Testing for mutations in homologous recombination repair genes is underused in patients with metastatic castration-resistant #prostateCancer . Published in JAMA Oncology and @cancertheradvsr. brnw.ch/21wJUxp #PCSM #mCRPC

Pablo Artista (Universidad 🏫) Black Hunter:

A JNCI study reports #ProstateCancer patients face an increased risk of mental health disorders compared with the general population. #MentalHealth support may increase the life expectancy of these patients. #pcsm Siqi Hu

Read here: oxford.ly/3wCri92

#ESTRO24 Piet Ost presenting outcomes of STORM randomized Ph II of MDT v ENRT for oligorecurrent prostate cancer #pcsm

✅ ENRT ⬆️BRFS, LRFS

MDT a/w 8-fold ⬆️ nodal recurrence 3➡️25%

Omitting PB ⬆️ local recurrences 3-fold (5➡️14%), but also increases GU2+ toxicity

Wishes for a great cause, building of a strong society, country and humanity..
Put in your hard #Labour !
Happy #Labour Day2024
Also
Happy #MaharashtraDay .. my birthplace.
Happy #MayDay2024 !
PCSM.

Great to see the first results of the PACE-C trial, acute toxicity presented today by the prolific Alison Tree 💙🇺🇦 👏Delighted to have made a contribution by recruiting patients to this trial Bon Secours Cork Cancer Centre CancerTrialsIreland 🌈 #PCSM 🇬🇧 🇮🇪 🇳🇿 and 🇨🇦 Dr. Andrew Loblaw

Dr. Alison Tree 💙🇺🇦 presented the first report of PACE-C acute toxicity results in intermediate to high-risk prostate cancer patients at #ESTRO24 . Learn more here. 🔽 #AccurayExpandRT #pcsm

Fantastic review of ongoing trials in prostate cancer #pcsm at the SCGCRC forum with Jun Gong Tanya Dorff Amar Kishan Rana McKay

Great to have several NRG Oncology trials open at Cedars-Sinai as well as phase 2 intermittent fasting trial from Stephen Freedland, MD Tanya Dorff

🚨 The most important plot in all of #radonc ?

ProtecT RCT 10-year RT vs RP #pcsm

Even with a *skeptical* prior, posterior prob true HR < 1 for RT vs RP is 56%!

RT is likely better than RP 🤩 🤩

'The future will probably be to treat not only one dominant intraprostatic nodule, but 2 or 3. And this is possible thanks to #CyberKnife .' Listen to Dr. Isa Bossi Zanetti from CDI Centro Diagnostico Italiano interviewed at #ISRSUSA2024 ! #AccurayExpandRT #pcsm ISRSy

Objective data to discuss duration of ADT in salvage/adjuvant setting #pcsm Amar Kishan Rahul Tendulkar, MD

📢 New findings in prostate cancer research! 🎗️ Baseline serum testosterone levels may guide the choice between bipolar androgen therapy (BAT) and enzalutamide for mCRPC patients. 🧬 Patients with high T levels might benefit more from BAT! 📊 #pcsm
rdcu.be/dIb1L

Giulio Francolini: Re-SBRT after previous definitive or salvage radiotherapy (RE-START): A report on the retrospective cohort.

At 302 patients, this is the largest study of which I am aware concerning prostate (70%) or prostate bed (30%) reirradiation!

#AIRO #PCSM #radonc

WATCH: Neal Shore (CURC) provides his initial impressions of the patient case, including an assessment of the patient's risk level and how this influences clinical decision-making. #mHSPC #PCSM

targetedonc.com/view/initial-i…

🚨Pelvic lymph node XRT improves survival for young men w/ #prostatecancer 🚨

Journal of Clinical Oncology ASCO

🗓️Median f/u 10.2 years, n=350

☢️For men <65 years WPRT improved
✅OS: HR 0.33
✅PCSM: HR 0.17

👉Post-hoc analysis of an RCT from 2005!!! Before any PSMA PET

Recently published data indicate that the Prolaris Test can accurately predict which patients may benefit from adding ADT to radiation therapy for prostate cancer. #pcsm #urology Jonathan Tward Huntsman Cancer Institute
GU Cancer Research Program @HuntsmanCancer
urologytimes.com/view/cell-cycl…

Thanks to Loyola professor (and UChicago #radonc residency alum) Abhi Solanki for his great talk on re-irradiation for radiorecurrent prostate cancer this morning! He also spoke with our residents about his work with the VA and the life lessons of improv comedy. #MedEd #pcsm

📣Our latest Clinical Oncology #PurpleJournal #OncoFlash article is out now, featuring:

✅SUNSET trial in lung #sabr Dr. David Palma
✅RT dose deescalation in oropharynx ca Nancy Lee
✅Ac-PSMA theranostics #pcsm
✅Metaanalysis of ICI toxicities

Read free 👉 clinicaloncologyonline.net/article/S0936-…

Grateful for our department RadOncUH under the leadership of Daniel E Spratt to receive a shoutout at the 2024 University Hospitals State of Research Address by Daniel I. Simon, M.D. highlighting the success of @Lauren_Henke & the The McClelland Lab!
#RadOnc #NAVAH #AdaptiveRT #bcsm #pcsm #KillCancer