Check out our latest covalent probes for imaging Staphylococcus aureus infections published J. Am. Chem. Soc.. Great work from Jeyun Jo and Tulsi Upadhyay and collaborators. pubs.acs.org/doi/full/10.10…

Check out our latest work targeting the malaria proteasome. Another outstanding collaboration with The Fidock Lab. Congrats to John Bennett and the other authors! pubs.acs.org/doi/10.1021/ac…

Check out our latest work on how we have used covalent macrocyclic inhibitors of the malaria proteasome to combat the growth of resistance. Big shout-out to The Fidock Lab Ryan Muir and everyone else who was a part of this story!

Check out my first first author research paper! We love covalency, and we hate malaria! We figured out a way to make covalent cyclic macrocycles that inhibit the malarial proteasome and can combat the growth of resistance to our inhibitors.

Super excited to be able to share our work in Nature Chemical Biology exploring the role of serine hydrolases in gut commensal bacteria! With taylor nguyen in KC Huang’s lab and many fantastic collaborators from the groups of Matthew Bogyo, Anthony O'Donoghue, Micah Niphakis, and Ami Bhatt, [1/4]

Check it out! Laura Keller’s masterpiece of her thesis work is finally in print. Great work and just in time for her graduation. nature.com/articles/s4158…

Make sure you see the live ratiometric surgery linked as a video at the end of the paper !

Fully funded PhD position in my lab UPF Medicine and Life Sciences. If you enjoy chembio and metabolic enzymes, apply!

Paper just published. That was fast! Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows - Faucher - Israel Journal of Chemistry - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/ij…

Our latest paper is out at bioRxiv. Great work from Franco Faucher and collaboration with Alex Adibekian. biorxiv.org/content/10.110…

Interesting ChemRxiv preprint by the Krusemark Lab. They report cyclic imines as electrophiles that undergo Mannich reactions at tyrosines and have potential for bioconjugation and covalent inhibitor development. doi.org/10.26434/chemr…

Interested in unraveling how the #microbiome modulates health and disease? Come join my new lab at Universität Jena!
We have two #PhDpositions in #ChemicalBiology
Synthesis: bit.ly/3JEjIwT
Biochemistry: bit.ly/3BP7D5T
#chemjobs #chemPhD #ChemTwitter #microverse_exc 1/3

Our first paper on our efforts mapping serine hydrolases in gut commensal bacteria is out. We identified a homolog of the human DPP4 protease in B. theta that is important for community fitness. biorxiv.org/content/10.110…

So excited to finally be sharing this story!! Thank you to the many collaborators (including taylor nguyen in KC Huang's lab, the teams of Anthony O'Donoghue, Micah Niphakis and Ami Bhatt, and my mentor Markus Lakemeyer) for helping me and Matthew Bogyo bring this story to life!

My work on understanding the impact of molecular design on the degradation behavior of degradable polymer semiconductors is out in J. Am. Chem. Soc. today! Thanks to all coauthors and Zhenan Bao for the support.
pubs.acs.org/doi/full/10.10…

Here’s our companion piece from the @mbogyob lab. We identify a class of covalent Mtb hydrolase inhibitors that inhibit bacterial growth. A great experience working with JSeeliger Lab and CellChemicalBiology to get these stories co-published. sciencedirect.com/science/articl…

It doesn’t matter if a Democrat or Republican is President, our immigration system is designed for cruelty towards and dehumanization of immigrants.

Immigration should not be a crime, and its criminalization is a relatively recent invention. This is a stain on our country.

After much hard work and a long time in the works, our paper on the roles of a family of serine hydrolases in T. gondii is out! Brett Babin Markus Lakemeyer Long Lab cell.com/cell-chemical-…