I'm overjoyed to present to #sciencetwitter our review covering the broad number of #extracellularmatrix interactions experienced by #neuralcrest cells. Most excitingly, we present #Hox genes as potential regulators of NCC-ECM interactions, with synergistic examples in the lit.
(1/3) Understanding the role of viscoelasticity in the Bone marrow (BM) niche.
Blood cells are produced by Haematopoietic stem cells (HSCs) in the BM niche. However, mutations in HSCs can cause the production of leukemic cells that alter the BM #ExtracellularMatrix (ECM).
In my #extracellularmatrix engineering class, I offered an extra credit assignment to make a meme (or graphical abstract) illustrating an ECM-related concept. The results brought me great joy, so I thought I'd share some of my favorites (all with permission).
Through the eyes of an #osteocyte . In #bone , this is what the environment of partially embedded osteocytes (osteoblastic–osteocytes) is like!
#Microscopy Monday #Microscopy ZEISS Microscopy #biology #imaging #biomineralization #extracellularmatrix
Read more:
doi.org/10.1007/s00223…
Hyaluronan sanıldığından çok daha önemli bir moleküldür. Daha gelişmenin en başlarında doku organizasyonunda ve hücre proliferasyonunda bir çok rolü vardır. #hyaluronan #ecm #extracellularmatrix #glycotime
📢🆕IUBMB Life Special Issue: 'Extracellular Matrix: The Dynamic Structural and Functional Network in Health and Disease'
Info:iubmb.onlinelibrary.wiley.com/pb-assets/asse…
#extracellularmatrix #cancer #immunology #Autophagy #cellsignalling #cellculture #macromolecules #pharmacological #organoids
Excited to share our #SingleCell #MultiTissue Dissection of #Obesity - #Exercise axis in #Adipose #Muscle tissues
biorxiv.org/content/10.110…
Central roles of #StemCells #Thermogenesis #ExtraCellularMatrix #Circadian #Tcells #CellCommunication
#scMetab #Metabolism #scWAT #vWAT #SkM
Fibronectin “records” insults associated with #innate immunity by undergoing a PTM citrullination that is subsequently “read” by resident #fibroblasts , suggesting that #inflammation primes #ExtracellularMatrix to support subsequent fibroblast activation. bit.ly/2PnJJUX
Check out our poster today at #SfN22 #SfN2022 . I will be from 2pm-7pm presenting our work on #extracellularmatrix and #microglia in a mouse model of #Parkinson 's disease
📍Board F29 - 2:00 PM (Poster 366.06)
Come say hi and let's talk about science! 🙂
#ExtraCellularMatrix #ArterialAging Sox9
#SmoothMuscleCell Sox9➡️ #ExtracellularVesicle (PLOD3)➡️ECM Stiffness➡️SMC #Senescence & likely #ArterialStiffening
+A feedforward loop
Senscence+ #MatrixStiffness ⏫Sox9 expression & nucleation
Senescent #SmoothMuscleCell , when seeded on…
Join us for the next DGZ, @DGZ.bsky.social Focus Workshop on #celladhesion and #extracellularmatrix , Tuesday April 30 at noon in Zoom, organized by Carsten Grashoff and Wickstrom-Lab. Speakers: Srishti Rangarajan Universität Münster, Ingo Thievessen, Dr. Amaia Cipitria, Julian Nüchel (PhD) ⬇️
Last but not least, we are introducing our speaker Gijsje Koenderink Gijsje Koenderink who will talk about her exciting work on the mechanics of the #ExtracellularMatrix . Join her talk and check out her group's website to find out more: tudelft.nl/en/faculty-of-…
OPEN POSTDOCTORAL POSITION at the Proteases and Extracellular Matrix Group eMatrix_GENYO GENYO #ExtracellularMatrix #ADAMTSproteases #uvealmelanoma 👇👇👇
Our paper on #ExtracellularMatrix ( #ECM ) deposition by #exosomes is out in JCellBiol.
#Caveolin -1 and #cholesterol play an essential role - thread below for details.
Congrats Look At, Inma, MechanoCaveoLab and collaborators Thanks Andrea Marat, PPdi Fiore, @rupress & CNIC
#Extracellularmatrix interaction with cell membrane receptors has mechanoresponsive effects on the #cytoskeleton to shield the nucleus from deforming & signals. Video & research by Zanetta Kechagia et al Pere Roca-Cusachs lab IBEC in Nature Methods. On bpod.org.uk/archive/2023/1…
A molecule to help avert heart disease, kidney damage, and stroke? Watch the SENS approach to one day getting aging under medical control. ow.ly/zGnq50LXIgC #extracellularmatrix #crosslinking #endingaging #glycoSENS #SENS #sensresearchfoundation #stroke
Come today at 14:15 to poster J07 at #IBRO2023 to chat about how different #ExtracellularMatrix contexts shape #microglia dynamics.
Work done with Mario FB and Irene Tomé at GlioMatrixLab and Ʌʗʜʋʗɑɼɼʘ.
Video shows Ncan-GFP (green) and IB4 microglia (magenta) in OTCs.
Looking forward to the keynote presentation by Wickstrom-Lab unraveling #stemcell fate and #extracellularmatrix #mechanics
DGMB ISMB BSMB Extracellular Matrix News
Our work about how #extracellularmatrix organization affects #neuroblastoma patients outcome. Using image analysis and #GraphTheory , we propose that #vitronectin creates migration tracks for malignant neuroblasts increasing tumour aggressiveness.
onlinelibrary.wiley.com/doi/10.1002/ij…
